T‐2 toxin promotes the proliferation of intestinal S. saprophyticus and facilitates its translocation to the liver in piglets and mice. The translocated bacteria trigger autophagy in Kupffer cells and recruit monocytes to the liver through the nucleotide‐binding oligomerization domain 2 (NOD2) signaling pathway, alongside the M1 polarization of hepatic
Yuanyuan Zhu+19 more
wiley +1 more source
Increased Cardiovascular Mortality in Hemodialysis: The Role of Chronic Inflammation, Complement Activation, and Non-Biocompatibility. [PDF]
Pethő ÁG+5 more
europepmc +1 more source
Tumor Microenvironment‐Responsive Nanomedicines for Potentiating Cancer Immunotherapy
Strategies for TME‐responsive Nanomaterials to Potentiate Cancer Immunotherapy. Abstract Immunotherapy has emerged as a transformative paradigm in oncology, yet its clinical efficacy remains constrained by the immunosuppressive tumor microenvironment and inadequate spatiotemporal control of existing modalities, resulting in suboptimal patient response ...
Qianqian Huang+7 more
wiley +1 more source
Defect in Sensing Human Thrombin by Porcine Endothelial Protease-Activated Receptor-1: Molecular Incompatibility Between Porcine PAR-1 and Human Thrombin. [PDF]
Hoang TX+6 more
europepmc +1 more source
Neonatal Hyperbilirubinemia: A Case of Complex Management Involving ABO Incompatibility, Sepsis, and Suspected G6PD Deficiency treated with Methyl Prednisolone. [PDF]
ZaiduMusa A+5 more
europepmc +1 more source
Maternal-Foetal HLA-DQB1 Incompatibility Is Associated With Pregnancy-Induced Hypertensive Disorders in a Genetically Isolated Population. [PDF]
Hof LJV+13 more
europepmc +1 more source
An Unusual Cause of Hexokinase 1 Deficiency-Case Report. [PDF]
Kilich G+15 more
europepmc +1 more source