Results 151 to 160 of about 10,075,883 (307)

Relationship between non-O blood groups and microvascular risk in type 2 diabetes. [PDF]

Diab Vasc Dis Res
Lurquin FO, Petit EL, Oriot P, Ahn SA, Hermans MP.   +4 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Prevalence of ABO Blood Groups and Their Relationship with Vascular Access Thrombosis and Mortality in Hemodialysis Patients. [PDF]

Medicina (Kaunas)
Hüzmeli C, Şeker A, Ortaç H, Yeral N.
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Authors' response to the commentary on "do certain blood groups increase COVID-19 severity and mortality?" [PDF]

Glob Epidemiol
Kitaw TA, Haile RN.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Revealing and quantifying polyclonal anti-A, B specificity in ABO histo-blood groups. [PDF]

Transfusion
Henry S, Perry H, Obukhova P, Tyrtysh T, Ryzhov I, Bovin N, Datta SS.   +6 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Immunity to α-Gal: The Opportunity for Malaria and Tuberculosis Control

Frontiers in Immunology, 2017
Alejandro Cabezas-Cruz, Alejandro Cabezas-Cruz, Alejandro Cabezas-Cruz, José de la Fuente, José de la Fuente   +4 more
doaj   +1 more source

Diabetes mellitus, ABO Blood groups, and biochemical correlates in pancreatic cancer- A retrospective study from Jeddah. [PDF]

J Family Med Prim Care
Aga SS, Khan MA, Thabet MS, Alharbi NM, Aljehani WM, Alhazmi AK, Alotaibi MF, Nissar S.   +7 more
europepmc   +1 more source