Results 81 to 90 of about 10,075,883 (307)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Immunogenicity of red blood cell blood group antigens in the population of Xi'an
Zhongguo shuxue zazhi[Objective] To evaluate the immunogenicity of red blood cell blood group antigens in the population of Xi'an. [Methods] Data on blood group antigens of voluntary blood donors from the Shaanxi Province Blood Center and unexpected antibody detection ...
ZHANG Liangzi +6 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Blood rheology adjustments in rats after a program of intermittent exposure to hypobaric hypoxia [PDF]
, 2013 Esteva, Santiago, Pere Panisello, Joan Ramon Torrella, Teresa Pagés, and Ginés Viscor. Blood rheology adjustments in rats after a program of intermittent exposure to hypobaric hypoxia. High Alt. Med. Biol. 10:275-281, 2009. Intermittent hypobaric hypoxia
Esteva i Gras, Santiago +4 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Which Blood Group is More Anemic: Five Years of Retrospective Experience [PDF]
, 2023 Aim: The relationship between blood groups and diseases has been a subject of interest for many researchers. This study aims to investigate the susceptibility of each blood group to anemia based on the relationship between the erythrocyte indices and the
Akidağı, Zeynep
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Laboratory analyses for evaluation of platelet disorders and platelet concentrates [PDF]
, 2006 High quality of platelet analytics requires specialized knowledge and skills. It was applied to analyze platelet activation and aggregation responses in a prospective controlled study of patients with Finnish type of amyloidosis.
Javela, Kaija
core
Distribution of clinically relevant erythrocyte antigens among blood donors of the Republic of Srpska [PDF]
Scripta Medica, 2015 Introduction: Identifying voluntary blood donors with rare phenotype characteristics is the basic precondition for creating a registry of blood donors with rare blood groups.
Guzijan Gordana +5 more
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source