Results 231 to 240 of about 7,093,189 (263)

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Cross-sectional associations of self-reported firearm use with blood lead concentrations in a nationally representative cohort of US adults. [PDF]

Environ Epidemiol
Day M, Braun JM, Hoover C.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Sociodemographic determinants and temporal variability of blood lead levels (2003-2019) in a pooled analysis of nine studies in four European countries. [PDF]

Sci Rep
Salamanca-Fernández E, Peinado FM, Esteban-López M, Puklova V, Poyatos RM, Govarts E, Laeremans M, Leermakers M, den Hond E, Schoeters G, Murawski A, Pedraza-Díaz S, Szigeti T, Verheyen V, Vogel N, Weber T, Hahn D, Zimmermann P, Kolossa-Gehring M, Fernandez MF, Arrebola JP.   +20 more
europepmc   +1 more source

Association between blood lead and gastrointestinal cancers among US adults: A cross-sectional study based on NHANES 2003-2016. [PDF]

Medicine (Baltimore)
Duan Y, Yang Y, Dang R, Dong C.
europepmc   +1 more source

Evidence for Genotype-Specific Optimal Blood Lead Levels for Cancer Risk: <i>MKI67</i> rs11016073 and <i>APOB</i> rs1367117 in a Female Prospective Cohort. [PDF]

Int J Mol Sci
Lubiński K, Marciniak W, Derkacz R, Kiljańczyk A, Kiljańczyk M, Lener MR, Pietrzak S, Cybulski C, Dębniak T, Huzarski T, Kluźniak W, Sulikowski T, Lubiński J, Scott RJ, Gronwald J.   +14 more
europepmc   +1 more source

Lead exposure in homes as modifying factors of blood lead levels among young children in Bihar, India. [PDF]

Environ Monit Assess
Nash E, Lu Y, Bose-O'Reilly S, Chandan AK, Nambiar L, Kushwaha M, Moonga G, Binkhorst G, Bhaskar K, Malik PS, Mehta S, Ghosh AK, Kumar A, Ali M, Srivastava A, Sanchez Ibarra G, Kass D.   +16 more
europepmc   +1 more source