Results 81 to 90 of about 5,451,783 (382)

Causal effects of blood lipids on amyotrophic lateral sclerosis: a Mendelian randomization study

bioRxiv, 2018
Amyotrophic lateral sclerosis (ALS) is a late-onset fatal neurodegenerative disorder that is predicted to increase across the globe by ~70% in the following decades.
P. Zeng, Xiaoping Zhou
semanticscholar   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Are (poly)phenols contained in 100% fruit juices mediating their effects on cardiometabolic risk factors? A meta-regression analysis

Frontiers in Nutrition, 2023
BackgroundThe consumption of 100% fruit juices has not been associated with substantial detrimental outcomes in population studies and may even contribute to improving the cardiometabolic profile if included in a healthy balanced diet.
Agnieszka Micek, Walter Currenti, Cristiana Mignogna, Alice Rosi, Ignazio Barbagallo, Ali A. Alshatwi, Daniele Del Rio, Pedro Mena, Justyna Godos   +8 more
doaj   +1 more source

On the interactions of lipids and proteins in the red blood cell membrane [PDF]

, 1970
The effects of temperature and of the action of a purified phospholipase C enzyme preparation on human red blood cell membranes has been investigated by chemical analyses, circular dichroism, and proton magnetic resonance measurements.
Chan, Sunney I., Glaser, Michael, Sheetz, Michael, Simpkins, Henry, Singer, S. J.   +4 more
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

The fatty acid composition of the lipids of some Pacific sardine tissues in relation to ovarian maturation and diet

Journal of Lipid Research, 1962
Gas-liquid chromatographic analyses of the C12 to C22 saturated and unsaturated fatty acids of lipids from Pacific sardine ovaries, mesenteric fat, whole blood, and planktonic eggs are presented and compared. Lipids from planktonic eggs and ovaries, with
Reuben Lasker, Gail H. Theilacker
doaj  

Association of apolipoprotein E gene polymorphisms with blood lipids and their interaction with dietary factors

Lipids in Health and Disease, 2018
Several candidate genes have been identified in relation to lipid metabolism, and among these, lipoprotein lipase (LPL) and apolipoprotein E (APOE) gene polymorphisms are major sources of genetically determined variation in lipid concentrations.
I. Shatwan, K. Winther, B. Ellahi, P. Elwood, Y. Ben-Shlomo, I. Givens, M. Rayman, J. Lovegrove, K. S. Vimaleswaran   +8 more
semanticscholar   +1 more source

Oxidative stress and blood lipid profile in Cameroonian obese subjects [PDF]

, 2008
The relationship between obesity, blood lipids and oxidative stress was investigated in 200 participants. The Body Mass Index of the subjects were positively correlated with the percentage body fat, the systolic and diastolic blood pressure, the fasting ...
Agbor, Gabriel A., Enyegue, Damaris M., Fomekong, Gilles I. D., Ngondi, Judith L., Oben, Julius E.   +4 more
core  

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration [PDF]

, 2011
AIMS: To evaluate the associations of emergent genome-wide-association study-derived coronary heart disease (CHD)-associated single nucleotide polymorphisms (SNPs) with established and emerging risk factors, and the association of genome-wide-association
Angelakopoulou, A, Berry, DJ, Casas, JP, Caulfield, M, Cooper, J, de Faire, U, Deanfield, J, Drenos, F, Fowkes, FG, Gigante, B, Hardy, R, Hingorani, AD, Humphries, SE, Hypponen, E, Ireland, H, Jefferis, BJ, Kivimaki, M, Kuh, D, Kumari, M, Lathrop, M, Laxton, RC, Leander, K, Maniatis, N, Marmot, M, Morris, RW, Motterle, A, Munroe, PB, Palmen, J, Power, C, Price, J, Samani, N, Shah, S, Shah, T, Simpson, IA, Smeeth, L, Sofat, R, Talmud, PJ, Thomson, A, Tzoulaki, I, Verzilli, C, Wallace, C, Whincup, PH, Whittaker, JC, Wong, A, Ye, S   +44 more
core   +2 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source