Results 241 to 250 of about 522,919 (310)

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Application value of auxiliary anterolateral hip mini-incision combined with traction-free reduction and internal fixation in complex intertrochanteric fractures in older adult patients. [PDF]

Front Surg
Gao Y, Chen K, Xiao M, Chen M.
europepmc   +1 more source

Hidden blood loss estimation using perioperative hemoglobin drop: agreement with the Sehat formula. [PDF]

BMC Surg
Ramadanov N, Heinz M, Prill R, Fuchs D, Becker R.   +4 more
europepmc   +1 more source

Rethinking intraoperative blood loss monitoring: a decision-oriented framework for clinically integrated assessment. [PDF]

Int J Burns Trauma
Bai J, Lu Y, Wang G, Zheng Q, Jia H, Dong Z, Zhang Y, Wang Z.   +7 more
europepmc   +1 more source

Postoperative Bleeding Definitions as the Foundation of Hemostasis in Pediatric Cardiac Surgery. [PDF]

Diagnostics (Basel)
Karam O, Atchison C, Chegondi M.
europepmc   +1 more source

Emergency Surgical Management of Ectopic Pregnancy Using Transvaginal NOTES (vNOTES) versus Laparoscopy: A Comparative Single-Surgeon Cohort Study. [PDF]

Int J Womens Health
Şahin T.
europepmc   +1 more source

[Reduction of surgical blood loss. Technics and procedures].

Revista brasileira de anestesiologia, 1972
openaire   +1 more source