Results 101 to 110 of about 3,348,978 (350)

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Relationship Between Surgery Timing and Hidden Blood Loss in Proximal Femoral Nailing of Pertrochanteric Fractures in Elderly Patients

Philippine Journal of Orthopaedics
Objectives. Pertrochanteric fractures, commonly incurred by the elderly from low-energy falls, require surgical management. Visible blood loss in the perioperative period is inconsistent with the big drop in hemoglobin seen postoperatively.
Martha Camille Dollete, Mickhael Langit, Joan Joseph Castillo, Allan Michael Brabante   +3 more
doaj   +1 more source

The Benefit of Sleeve Gastrectomy in Obese Adolescents on Nonalcoholic Steatohepatitis and Hepatic Fibrosis [PDF]

, 2017
Objective To determine whether bariatric surgery is effective for the treatment of nonalcoholic steatohepatitis (NASH) in adolescence, we compared the efficacy of laparoscopic sleeve gastrectomy (LSG) with that of lifestyle intervention (nonsurgical ...
Alisi, Anna, Baumann, Ulrich, Caccamo, Romina, Cutrera, Renato, De Peppo, Francesco, De Stefanis, Cristiano, Giordano, Ugo, Manco, Melania, Mosca, Antonella, Nobili, Valerio, Silecchia, Gianfranco   +10 more
core   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Predicting intraoperative major blood loss in microsurgery for brain arteriovenous malformations

Frontiers in Medicine
ObjectiveIntraoperative blood loss poses a great challenge for brain arteriovenous malformation (AVM) microsurgery, although systematic researches are still lacking. This study aimed to identify factors predicting intraoperative major blood loss in brain
Jichun Shi, Shuangxiang Xu, Yu Feng, Wei Wei, Yichun Zou, Wenping Xiong, Wenyuan Zhao, Tingbao Zhang, Hao Peng, Hao Peng, Jincao Chen   +10 more
doaj   +1 more source

Оптимизация инфузионной терапии при операциях на печени [PDF]

, 2011
Рішення проблеми крововтрати при великих резекціях печінки є завданням як хірургів, так і анестезіологів. У статті наведені результати застосування методики «малооб’ємної» інфузійної терапії на обсяг і інтенсивність інтраопераційної крововтрати ...
Гусак, И.В., Козлова, Т.В., Скорый, Д.И.   +2 more
core  

Changes in the Blood Picture in Pregnancy, Deli­very, and Puerperium, Particulary Centering Around the Blood Loss During Delivery [PDF]

, 1957
For the periods ranging from the fifth gravid month to the sixth post partum week continuous examinations were conducted on the blood picture of 10 multiparas and 18 primipars who came to the Second Maternity Hospita, Okayama University Medical School ...
Fujimori, Hiroshi
core   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Application of high-dose tranexamic acid in the perioperative period: a narrative review

Frontiers in Pharmacology
ObjectiveTo investigate the efficacy and safety of high-dose tranexamic acid in different types of surgeries and provide a reference for clinical practice.MethodsWe systematically searched PubMed, Cochrane Library, Science, Embase, and CNKI databases ...
Yushan Duan, Xiaohong Wan, Yiming Ma, Weihua Zhu, Yue Yin, Qingqing Huang, Yuan Yang   +6 more
doaj   +1 more source