Results 21 to 30 of about 209,915 (212)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Agreement Between Pulse Oximetry and Measured Arterial Oxygen Saturations in Postoperative Functionally Univentricular Patients

open access: yesChildren
Background: Pulse oximetry is widely used to estimate arterial oxygen saturation, yet accuracy may vary for a number of reasons. Data on children with functionally univentricular circulation are limited.
Fabio Savorgnan   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

RANCANG BANGUN ALAT PENDETEKSI GOLONGAN DARAH DAN SATURASI OKSIGEN BERBASIS ARDUINO UNO

open access: yesEdusaintek, 2023
In this study a device was designed to detect human blood group using the ABO method which is integrated with a blood oxygen saturation meter. This tool can detect agglutination or non-agglutination reactions in blood samples that have been treated with
Ahmad Halim   +2 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

open access: yesAdvanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng   +20 more
wiley   +1 more source

Compraistion of Blood Oxygen Saturation in Healthy Anterior Teeth with Ear

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2007
Introduction: Neural based tests response have some limitations. In this years pulse oximetery have used to measure oxygen saturation of pulpal blood circulation.
N Kaviani, B Mosavia, H Vahedi
doaj  

Unique Role of Microstructure of a Bioimplant Zinc Alloy and Protein Content of Simulated Body Fluid in Corrosion and Fracture

open access: yesAdvanced Functional Materials, EarlyView.
BSA addition to physiological solutions enhances resistance of a Zn alloy to stress corrosion cracking (SCC) but reduces its corrosion resistance. Extended surface characterization explains the contrasting influences on corrosion and SCC. Unexpectedly, the alloy suffers transgranular SCC (TGSCC), despite extensive grain boundary precipitation. Thorough
RK Singh Raman   +9 more
wiley   +1 more source

Comparison of Pulse and Arterial Oxygen Saturation Changes in Endotracheal Suction Opening with Two Sizes of 12 and 14: A Randomised Controlled Trial

open access: yesمراقبت پرستاری و مامایی ابن سینا, 2017
Introduction: Artificial airway stimulates the sympathetic system and the loss of ciliated cells and the accumulation of secretions. Therefore, since these patients do not have the ability to discharge, periodic suction is needed.
Akvan Paymard   +4 more
doaj  

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