Results 101 to 110 of about 5,193,002 (344)

KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. [PDF]

, 2014
Preventing relapses of Plasmodium vivax malaria through a radical cure depends on use of the 8-aminoquinoline primaquine, which is associated with safety and compliance issues.
Borboa, Rachel, Campo, Brice, Chatterjee, Arnab K, Chen, Zhong, Diagana, Thierry T, Gagaring, Kerstin, Glynne, Richard J, Klooster, Els J, Kocken, Clemens HM, Kuhen, Kelli, Leroy, Didier, Luty, Adrian, McNamara, Case W, Nagle, Advait, Plouffe, David M, Remarque, Edmond J, Roland, Jason, Sauerwein, Robert, Thomas, Alan W, van Amsterdam, Sandra M, van den Berg, Alexander, van Gemert, Geert-Jan, Voorberg-van der Wel, Annemarie, Winzeler, Elizabeth A, Yeung, Bryan KS, Zeeman, Anne-Marie   +25 more
core   +1 more source

A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites

Science, 2020
An artemisinin resistance mechanism Species of the malaria parasite Plasmodium live in red blood cells and possess a highly conserved gene called kelch13.
Jakob Birnbaum, Sarah Scharf, S. Schmidt, Ernst Jonscher, W. Hoeijmakers, Sven Flemming, C. G. Toenhake, Marius Schmitt, Ricarda Sabitzki, Bärbel Bergmann, Ulrike Fröhlke, P. Mesén-Ramírez, Alexandra Blancke Soares, Hendrik Herrmann, R. Bártfai, T. Spielmann   +15 more
semanticscholar   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Tick identification and studies of blood parasites in Camels using microscopic and molecular techniques, with special reference to biological control by Metarhizium anisopliae [PDF]

Journal of Bioscience and Applied Research
Recognizing the economic importance of Camelus dromedarius underscores the need for attention to parasitic diseases that threaten their health and productivity, particularly blood parasites and ticks.
Nabawia Elhadidy, Eman Elkelesh, Nahed. Emam, yasmin Mohamed   +3 more
doaj   +1 more source

Haematoxenus separatus sp. n. (Sporozoa, Theileriidae) a new tickborne blood parasite of domestic sheep in Tanzania [PDF]

, 1974
Après une revue du genre Haematoxenus, connu chez le bovin, le buffle africain et des antilopes africaines, les auteurs rapportent la découverte d'une nouvelle espèce de ce genre chez le mouton domestique en Tanzanie, H. separatus sp. n.
Andreasen, M.P., Uilenberg, Gerrit
core  

Malaria vaccines 1985-2005: a full circle?

, 2005
Few who were actively engaged in malaria vaccine research 20 years ago (including myself) would have imagined that, in 2005, there would still be a prediction of a 10-20-year horizon before vaccines become part of malaria-control strategies.
Targett, Geoffrey A
core   +1 more source

Blood Parasites of Camels from Central Regions of Iran: Comparative Evaluation of Various Detection Techniques and Serum Protein Components

, 2015
| The 227 blood samples of camels (male: 130, female: 97) were examined from different regions of central areas of Iran between March 2011 and April 2012.
A. Karimi
semanticscholar   +1 more source

Soft Ionic and Electronic Triboelectric Nanogenerators: Toward Attachable and Implantable Biomedical Applications

Advanced Materials, EarlyView.
This review provides an overview of triboelectric nanogenerator (TENG)–based biomedical applications by classifying studies into electronic and ionic systems across attachable and implantable platforms. It summarizes key material choices, device structures, and working mechanisms that characterize current TENG‐based research, and outlines six future ...
Kyongtae Choi, Jimin Park, Won Jun Song, Soohwan An, Seonggyu Choe, Byeong‐Rak Keum, Min Young Kim, Dae Hee Hwang, Young‐Geun Park, Sung‐Won Kim, Sangyul Baik, Gwang‐Bum Im, Younghoon Lee   +12 more
wiley   +1 more source

Engineered Heparinized GQDS/HPEI–Polyamide Membrane for Bilirubin Removal via One Step Anti Coagulation

Advanced Materials Interfaces, EarlyView.
A multifunctional heparinized polyamide membrane embedded with graphene quantum dots (GQDs) and hyperbranched polyethyleneimine (HPEI) is engineered for efficient bilirubin removal via a one‐step anticoagulation–adsorption process. The membrane demonstrates enhanced hemocompatibility, prolonged clotting times, and high bilirubin adsorption capacity ...
Abdur Rehman Mushtaq Ahmad, Maria Wasim, Aneela Sabir, Muhammad Shafiq, Syed Abdul Basit Shah, Maoz Maoz, Vanni Lughi   +6 more
wiley   +1 more source

A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern [PDF]

, 2003
The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors.
Sue A. Kyes, Zoe Christodoulou, Ahmed Raza, Paul Horrocks, Robert Pinches, J. Alexandra Rowe, Chris I. Newbold, Aguiar, Baruch, Beeson, Berendt, Bonnefoy, Brabin, Buffet, Bull, Chen, Chen, Church, Duffy, Fidock, Fowler, Freitas-Junior, Fried, Fried, Fried, Gardner, Gardner, Goda, Kyes, Kyes, Lambros, Lekana Douki, Marsh, Newbold, Pouvelle, Reeder, Ricke, Roberts, Robson, Rowe, Rowe, Rubio, Salanti, Scherf, Smith, Smith, Smith, Su, Taylor, Trager, Vazquez-Macias, Voss   +51 more
core   +1 more source