Results 101 to 110 of about 2,574,493 (304)

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source

Prevalence of blood parasites in Tyrannidae (flycatchers) in the Eastern plains of Colombia

Memorias do Instituto Oswaldo Cruz, 2004
Blood samples from 159 birds of the New-world family Tyrannidae (the flycatchers) from the eastern plains of Colombia, were examined for haematozoa parasites, in 1999-2000. Haematozoa were detected in six of 20 species.
Nubia E Matta, Natalia Basto, Rafael Gutierrez, Oscar A Rodríguez, Ellis C Greiner   +4 more
doaj   +1 more source

Experimental vaccination by single dose sporozoite injection of blood-stage attenuated malaria parasites. [PDF]

Malaria vaccination approaches using live Plasmodium parasites are currently explored, with either attenuated mosquito-derived sporozoites or attenuated blood-stage parasites. Both approaches would profit from the availability of attenuated and avirulent
Steinbrück, Smilla, Janse, Chris J, Sattler, Julia M, Jäcklin, Martin, Hentzschel, Franziska, Fischer, Manuel, Frischknecht, Friedrich, Moreau, Catherine A, Zheng, Xinyu, Abdelrahim, Aiman, Hoffmann, Angelika, Keiber, Lukas, Zechel, Luisa   +12 more
core   +2 more sources

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source

Replication of asexual blood stage parasites is unaffected in Plrx(-) mutant parasites.

, 2013
(A) In vivo growth curves of WT and Plrx(-) parasites. Five and six naïve animals were injected intravenously with 1,000 WT and Plrx(-) parasites, respectively.
Katja Becker (13669), Stefan Rahlfs (13665), Kai Matuschewski (118), R. Heiner Schirmer (49837), Kathrin Buchholz (49836)   +4 more
core   +1 more source

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

Advanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Blood Parasites in Relation to Pheasants and Quail in Iowa [PDF]

, 1962
Blood parasite investigations of ring-necked pheasants (Phasianus colchicus) and bobwhite (Colinus virginianus) were conducted in Iowa during 1957-59 and 1959-61.
Fore, Paul L., Roslien, David J., Haugen, Arnold O.   +2 more
core   +1 more source

Molecular and morphological characterization of one known and three new species of fish parasitic Trypanosoma Gruby, 1972 from the south coast of South Africa

Parasitology
The genus Trypanosoma Gruby, 1843 encompasses unique, flagellate haemoparasites infecting all vertebrate classes globally (excluding Antarctica). While trypanosomes in terrestrial mammals are well-studied due to their medical and veterinary significance,
Chandra Le Roux, Courtney A. Cook, Edward C. Netherlands, Marliese Truter, Nico J. Smit   +4 more
doaj   +1 more source

A Metal‐Polyphenol Self‐Assembled Coated 3D Sponge With Mild Photothermal Antibacterial, Exudate‐Controlling, and Immunomodulatory Functions for Hemostasis and Chronic Wound Healing

Advanced Science, EarlyView.
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang, Feng Qin, Xiaomeng Zhang, Xueqin Shuang, Jiahua Zhou, Ming Cheng, Baicheng Lu, Mingyue Song, Yuntian Bai, Dianying Zhang, Ming Li, Yanhua Wang   +11 more
wiley   +1 more source