Results 121 to 130 of about 7,072,300 (361)
Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay +12 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos +17 more
wiley +1 more source
Central Dysmyelination in SSADH‐Deficient Humans and Mice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer +11 more
wiley +1 more source
DEVELOPMENT AND VALIDATION OF IMMUNOASSAY FOR IMMUNOGENICITY OF INTERFERON-ALPHA 2A DRUGS
Разработка и регистрация лекарственных средств, 2019 Interferons were one of the first groups of cytokines to be cloned and produced in bacteria. Interferon-based drugs are widely used for treatment of various infections, inflammatory and autoimmune diseases and malignant tumors.
E. V. Mityushova +4 more
doaj
BLOOD VOLUME IN CLINICAL SHOCK. I. MIXING TIME AND DISAPPEARANCE RATE OF T-1824 IN NORMAL SUBJECTS AND IN PATIENTS IN SHOCK; DETERMINATION OF PLASMA VOLUME IN MAN FROM 10-MINUTE SAMPLE12 [PDF]
, 1946 Robert P. Noble +3 more
openalex +1 more source
Efgartigimod Combined With Steroid Treatment for HAM/TSP: A Case Report
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurological disorder with limited treatment options. We report a 54‐year‐old female with decade‐long, progressive HAM/TSP, previously refractory to rituximab, who experienced worsening spastic paraparesis and neurogenic bladder dysfunction.
Jiahui Zeng +5 more
wiley +1 more source
Influence of Dialysis of the Blood Plasma on the Growth of Tissue in vitro
, 1940 Moriaki Tazima
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang +16 more
wiley +1 more source
The carbon dioxide carrying power of the constituents of plasma. The alkali reserve of blood
, 1920 John Mellanby, Callie J. Thomas
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