Results 151 to 160 of about 8,163,421 (306)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Near-infrared spectroscopy of blood plasma amino acids with chemometrics towards breast cancer discrimination. [PDF]

Transl Oncol
Zhu L, Li H, Qian W, Li C, Huang C, Zhang Y, Duan Y, Wang S, Xu Y, Zhang J, Liu M, Li X, Zhao S, Pan W.   +13 more
europepmc   +1 more source

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti, Marta Miola, Liliana Liverani, Paolo Sartori, Enrica Verné, Aldo R. Boccaccini   +5 more
wiley   +1 more source

Retinal microvascular alterations in Alzheimer's disease: Linking blood plasma biomarkers and cerebral small vessel pathology. [PDF]

Alzheimers Dement
Kwapong WR, Wu N, Lin W, Shen J, Wang Y, Qian J, Wen C, Luan X, Liu Y, Cheng H, Qiu H, Cheung CY, Zheng C, Liu Y, Yang Y, Mok V, Wang Z.   +16 more
europepmc   +1 more source

Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial.

Journal of the American Medical Association (JAMA), 2015
J. Holcomb, B. Tilley, S. Baraniuk, E. Fox, C. Wade, J. Podbielski, D. D. del Junco, K. Brasel, E. Bulger, R. Callcut, M. Cohen, B. Cotton, T. Fabian, K. Inaba, J. Kerby, P. Muškát, T. O'keeffe, S. Rizoli, B. Robinson, T. Scalea, M. Schreiber, D. Stein, J. Weinberg, J. Callum, J. Hess, N. Matijevic, Christopher N. Miller, J. Pittet, D. Hoyt, G. Pearson, B. Leroux, G. van Belle   +31 more
semanticscholar   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Structural and conformational rearrangements of human serum albumin, transferrin, and blood plasma induced by carbosilane dendrimer therapeutic delivery system. [PDF]

Sci Rep
Zawadzki S, Okła E, Michlewska S, Makowski T, Buczkowski A, López PO, de la Mata FJ, Ionov M, Bryszewska M, Miłowska K.   +9 more
europepmc   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Molecular spectroscopy of blood plasma differentiates metabolic dysfunction-associated steatohepatitis from steatosis. [PDF]

J Transl Med
Nováková B, Vrtělka O, Králová K, Habartová L, Šmíd V, Dvořák K, Petrtýl J, Žížalová K, Stříteský J, Vítek L, Leníček M, Setnička V, Brůha R.   +12 more
europepmc   +1 more source

Ascorbate is an outstanding antioxidant in human blood plasma.

Proceedings of the National Academy of Sciences of the United States of America, 1989
B. Frei, L. England, B. Ames
semanticscholar   +1 more source