Results 271 to 280 of about 420,739 (331)
Advanced Science, EarlyView.Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun +15 more
wiley +1 more source
Flavonolignans inhibit the arachidonic acid pathway in blood platelets. [PDF]
BMC Complement Altern Med, 2017 Bijak M, Saluk-Bijak J.
europepmc +1 more source
Advanced Science, EarlyView.Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu +7 more
wiley +1 more source
Mitochondrial functioning abnormalities observed in blood platelets of chronic smoke-exposed guinea pigs - a pilot study. [PDF]
Int J Chron Obstruct Pulmon Dis, 2018 Białas AJ +9 more
europepmc +1 more source
Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines
Advanced Science, EarlyView.This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li +11 more
wiley +1 more source
Human blood platelets and viruses: defense mechanism and role in the removal of viral pathogens. [PDF]
Thromb J, 2018 Seyoum M, Enawgaw B, Melku M.
europepmc +1 more source
METABOLISM, TRANSFER AND STORAGE OF 5‐HYDROXYTRYPTAMINE IN BLOOD PLATELETS*
, 1968 A. Pletscher
openalex +1 more source
Advanced Science, EarlyView.A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei +13 more
wiley +1 more source
Correction to: Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critically ill patients? [PDF]
Ann Intensive Care, 2018 Dewitte A +6 more
europepmc +1 more source
Platelet-rich plasma preparation using three devices: Implications for platelet activation and platelet growth factor release [PDF]
, 2006 BOX, HAM +6 more
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