Results 321 to 330 of about 4,844,363 (388)

Trimetallic Nanozyme‐Embedded Smart Hydrogel Enables NIR‐Controlled Bacterial Killing and Oxidative Stress Alleviation

Advanced Science, EarlyView.
A microenvironment‐responsive hydrogel is developed incorporating polymyxin B‐modified AuMnCu nanozymes and dual drugs (tannic acid and tobramycin). At infection sites, it generates ROS, releases drugs responsively, and enhances mild photothermal action to disrupt bacterial redox balance.
Zehui Xiao, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +5 more
wiley   +1 more source

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

Advanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang, Yirong An, Shiran Tao, Shenao Qu, Minge Wu, Guantong Fang, Ziqing Chen, Weilun Song, Haoze Leng, Rongqian Wu, Yi Lyu, Xiaoli Liu, Dinghui Dong   +12 more
wiley   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Blood platelets.

Science progress, 1979
openaire   +1 more source

Reversible formation of von-Willebrand-factor-platelet aggregates in microvascular blood flow. [PDF]

PNAS Nexus
Topuz A, Hoore M, Gompper G, Fedosov DA.
europepmc   +1 more source

Arterial human blood flow can be stopped by cables of VWF and platelets without coagulation. [PDF]

Blood Adv
Machenaud ELV, Weisel JW, Litvinov RI, Nagaswami C, Ku DN.   +4 more
europepmc   +1 more source

G-CSF primed bone marrow for autologous transplantation: rapid recovery of neutrophils and platelets comparable to that of peripheral blood stem cell transplantation

, 1997
RM Lowenthal, KA Marsden, NN Kotlovsky
openalex  

Cost-Effectiveness of Cryopreserved vs Liquid-Stored Platelets for Managing Surgical Bleeding.

JAMA Netw Open
Orman Z, Reade MC, Marks DC, Howe BD, Bailey M, Carrandi A, McQuilten ZK, Higgins AM.   +7 more
europepmc   +1 more source

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Blood platelet biochemistry

Thrombosis Research, 2012
Defects in platelet function or formation increase the risk for bleeding or thrombosis, which indicates the crucial role for platelets in maintaining haemostasis in normal life. Upon vascular injury, platelets instantly adhere to the exposed extracellular matrix which results in platelet activation and aggregation and the formation a haemostatic plug ...
Katleen, Broos, Simon F, De Meyer, Hendrik B, Feys, Karen, Vanhoorelbeke, Hans, Deckmyn   +4 more
openaire   +2 more sources

Blood Platelets and Platelet Transfusions

Archives of Internal Medicine, 1961
The application of quantitative biological and biochemical methods to the study of the blood platelets has led to revolutionary developments in our understanding of these elusive structures. 1 Until recently platelets were often regarded as non-cellular in nature, although it has long been known that they are of cellular origin.
openaire   +2 more sources