Results 111 to 120 of about 10,112,832 (405)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Insufficiency of the zona glomerulosa of the adrenal cortex and progressive kidney insufficiency following unilateral adrenalectomy – case report and discussion

Blood Pressure, 2018
Background: Primary aldosteronism (PA) is the most common cause of secondary hypertension and bilateral adrenal hyperplasia (BAH) and aldosterone-producing adenoma (APA) seem to be the most common causes of PA.
Joanna Kanarek-Kucner, Adrian Stefański, Rufus Barraclough, Tomasz Gorycki, Jacek Wolf, Krzysztof Narkiewicz, Michał Hoffmann   +6 more
doaj   +1 more source

Tobacco and the Blood-pressure [PDF]

The American Journal of the Medical Sciences, 1914
n ...
openaire   +3 more sources

Blood Pressure, Blood Flow and Intraocular Pressure

Ophthalmic Research, 1974
(1) A rise of blood pressure by steps between 80 and 180 mm Hg mean pressure did not cause an increase in intraocular pressure under the conditions which are mentioned above.
W. Baumgart, U. Metzler, D. Kaskel, H. Fink   +3 more
openaire   +2 more sources

Does coffee consumption alter plasma lipoprotein(A) concentrations? A systematic review [PDF]

, 2018
Coffee consumption alters plasma lipid and cholesterol concentrations, however, its effects on lipoprotein(a) (Lp(a)) have received little study. The aim of this PRISMA compliant systematic review was to examine the role of coffee on serum Lp(a).
Banach, Maciej, Meta-Analysis, Lipid Blood Pressure, Penson, Peter, Serban, Maria-Corina, Ursoniu, Sorin   +4 more
core   +1 more source

Blood Pressure Measurement in SPRINT (Systolic Blood Pressure Intervention Trial)

HYPERTENSION, 2018
Recent publications have stated that the blood pressure (BP) measurement technique used in SPRINT (Systolic Blood Pressure Intervention Trial) was unattended. However, the SPRINT protocol does not address the issue of attendance.
K. Johnson, P. Whelton, W. Cushman, J. Cutler, G. Evans, Joni K. Snyder, W. Ambrosius, S. Beddhu, A. Cheung, Lawrence J. Fine, C. Lewis, Mahboob Rahman, D. Reboussin, M. Rocco, S. Oparil, J. Wright   +15 more
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Evidence-based proposal for the number of ambulatory readings required for assessing blood pressure level in research settings: an analysis of the IDACO database

Blood Pressure, 2018
Background: Guidelines on the required number of ambulatory blood pressure (ABP) readings focus on individual patients. Clinical researchers often face the dilemma of applying recommendations and discarding potentially valuable information or accepting ...
Wen-Yi Yang, Lutgarde Thijs, Zhen-Yu Zhang, Kei Asayama, José Boggia, Tine W. Hansen, Takayoshi Ohkubo, Jørgen Jeppesen, Katarzyna Stolarz-Skrzypek, Sofia Malyutina, Edoardo Casiglia, Yuri Nikitin, Yan Li, Ji-Guang Wang, Yutaka Imai, Kalina Kawecka-Jaszcz, Eoin O’Brien, Jan A. Staessen   +17 more
doaj   +1 more source

Estimating coupling directions in the cardio-respiratory system using recurrence properties [PDF]

, 2013
The asymmetry of coupling between complex systems can be studied by conditional probabilities of recurrence, which can be estimated by joint recurrence plots. This approach is applied for the first time on experimental data: time series of the human cardio-respiratory system in order to investigate the couplings between heart rate, mean arterial blood ...
arxiv   +1 more source

Evaluation of the Linear Relationship Between Pulse Arrival Time and Blood Pressure in ICU Patients: Potential and Limitations [PDF]

, 2018
A variety of techniques based on the indirect measurement of blood pressure (BP) by Pulse Transit Time (PTT) have been explored over the past few years.
Braiam Escobar-Restrepo, Braiam Escobar-Restrepo, Panayiotis A. Kyriacou, Robinson Torres-Villa   +3 more
core   +2 more sources