Results 41 to 50 of about 8,910,389 (314)
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
ARYA Atherosclerosis, 2010 Introduction: Obesity is an independent risk factor for cardiovascular disease. Several clinical studies have shown that blood pressure decreases significantly with reduction of body weight.
Alireza Khosravi +2 more
doaj
Blood Pressure, 2019 Purpose: The study was designed to evaluate clinical and laboratory determinants pulse wave velocity (PWV) ratio in women at the age of 50–65 years without overt cardiovascular disease but having elevated cardiovascular risk, such as hypertension ...
Agne Laucyte-Cibulskiene +5 more
doaj +1 more source
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
Nature Genetics, 2018 In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis.
Ayush Giri +101 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
A sleep apnoea questionnaire predicts organ damage in hypertensive patients
Blood Pressure, 2019 Background: Arterial hypertension is associated with obstructive sleep apnoea, poor quality and duration of sleep, which might contribute to hypertension-mediated organ damage.
Valeria Bisogni +10 more
doaj +1 more source
Blood pressure variability: clinical relevance and application
The Journal of Clinical Hypertension, 2018 Blood pressure variability is an entity that characterizes the continuous and dynamic fluctuations that occur in blood pressure levels throughout a lifetime.
G. Parati +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Comparison of arterial stiffness indices measured by pulse wave velocity and pulse wave analysis
Blood Pressure, 2019 Objective: Arterial stiffness indices measured by pulse wave velocity and pulse wave analysis have been widely studied in different populations. Only a few small studies have been reported regarding these two measurement methods.
Hongyan Zhu +13 more
doaj +1 more source
British medical journal, 2009 Objectives To determine the quantitative efficacy of different classes of blood pressure lowering drugs in preventing coronary heart disease (CHD) and stroke, and who should receive treatment. Design Meta-analysis. Data source Medline (1966-2007).
M. Law, J. Morris, N. Wald
semanticscholar +1 more source