Results 71 to 80 of about 10,715,394 (405)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Influence of Lavender Aroma Therapy on Decreasing Blood Pressure in Hypertension Patients [PDF]

, 2016
The objective of this research was to determine the influence of lavender aromatherapy on decreasing blood pressure in hypertension patients. The research employed quantitative method with quasi experiment design.
Ginting, S. (Surita), Gultom, A. B. (Agustina), Silalahi, E. L. (Elni)   +2 more
core  

Life events and acute cardiovascular reactions to mental stress: a cohort study [PDF]

, 2005
Objective: This study addressed the issue of whether frequent exposure to life events is associated with aggravation or blunting of cardiovascular reactions to acute mental stress.
Carroll, Douglas, Phillips, Anna C., Ring, Christopher, Sweeting, Helen, West, Patrick   +4 more
core   +1 more source

Panethnic Differences in Blood Pressure in Europe: A Systematic Review and Meta-Analysis

PLoS ONE, 2016
Background People of Sub Saharan Africa (SSA) and South Asians(SA) ethnic minorities living in Europe have higher risk of stroke than native Europeans(EU).
P. Modesti, G. Reboldi, F. Cappuccio, C. Agyemang, G. Remuzzi, S. Rapi, Eleonora Perruolo, G. Parati   +7 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Accuracy of pulse interval timing in ambulatory blood pressure measurement [PDF]

, 2016
Blood pressure (BP) monitors rely on pulse detection. Some blood pressure monitors use pulse timings to analyse pulse interval variability for arrhythmia screening, but this assumes that the pulse interval timings detected from BP cuffs are accurate ...
Blake, James R., Kane, Sarah A., Langley, Philip, McArdle, Frank J., Sims, Andrew J.   +4 more
core   +1 more source

Nicotinamide Riboside Supplementation for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Midlife and Older Adults [PDF]

, 2022
Kaitlin A. Freeberg, Daniel H. Craighead, Christopher R. Martens, Zhiying You, Michel Chonchol, Douglas R. Seals   +5 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Loop Gain as a Predictor of Blood Pressure Response in Patients Treated for Obstructive Sleep Apnea: Secondary Analysis of a Clinical Trial [PDF]

, 2023
Christopher N. Schmickl, Jeremy E. Orr, Scott A. Sands, Raichel M. Alex, Ali Azarbarzin, L. Mcginnis, Stephanie White, Diego R. Mazzotti, Brandon Nokes, Robert L. Owens, Daniel J. Gottlieb, Atul Malhotra   +11 more
openalex   +1 more source

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Nature Genetics, 2018
In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis.
Ayush Giri, J. Hellwege, Jacob M. Keaton, Jihwan Park, Chengxiang Qiu, H. Warren, E. Torstenson, C. Kovesdy, Yan V. Sun, O. Wilson, C. Robinson-Cohen, C. Roumie, C. Chung, K. Birdwell, S. Damrauer, S. Duvall, D. Klarin, Kelly Cho, Yu Wang, E. Evangelou, C. Cabrera, L. Wain, Rojesh Shrestha, Brian S. Mautz, Elvis Akwo, M. Sargurupremraj, S. Debette, M. Boehnke, L. Scott, J. Luan, Jinghua Zhao, Sara M. Willems, S. Thériault, Nabi Shah, C. Oldmeadow, P. Almgren, Ruifang Li-Gao, N. Verweij, Thibaud S. Boutin, M. Mangino, I. Ntalla, E. Feofanova, P. Surendran, J. Cook, Savita Karthikeyan, N. Lahrouchi, Chunyu Liu, N. Sepúlveda, T. Richardson, A. Kraja, P. Amouyel, M. Farrall, N. Poulter, M. Laakso, E. Zeggini, P. Sever, R. Scott, C. Langenberg, N. Wareham, D. Conen, C. Palmer, J. Attia, D. Chasman, P. Ridker, O. Melander, D. Mook-Kanamori, P. Harst, F. Cucca, D. Schlessinger, C. Hayward, T. Spector, M. Jarvelin, B. Hennig, N. Timpson, Wei-Qi Wei, Joshua C. Smith, Yaomin Xu, M. Matheny, E. Siew, C. Lindgren, K. Herzig, G. Dedoussis, J. Denny, B. Psaty, J. Howson, P. Munroe, C. Newton‐Cheh, M. Caulfield, P. Elliott, J. Gaziano, J. Concato, P. Wilson, P. Tsao, D. V. Velez Edwards, K. Suszták, C. O’Donnell, A. Hung, T. Edwards, Understanding Society Scientific Group, International Consortium for Blood Pressure, Blood Pressure-International Consortium of Exome Chip Studies, Million Veteran Program   +101 more
semanticscholar   +1 more source