Results 61 to 70 of about 1,063,498 (305)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Pengaruh Ukuran Manset Terhadap Hasil Pengukuran Tekanan Darah [PDF]

, 2009
Correct blood pressure measurements are essential to diagnosing and treating high blood pressure. Several factors influence blood pressure measurements and the factor which is often neglected by the medical professionals is the cuff size inappropriate to
Aryani, E. (Evelyn), Suherman, J. (Jo)
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Home Blood Pressure Measurement and Self-Interpretation of Blood Pressure Readings During Pregnancy: Hy-Result e-Health Prospective Study

Vascular Health and Risk Management, 2022
Nicolas Postel-Vinay,1,2 Jiali-Delphine Shao,3 Anne Pinton,4 Aude Servais,5 Nicole Gebara,1 Laurence Amar1 1Hypertension Unit, ESH Excellence Center, Hôpital Européen Georges Pompidou, APHP, Paris, France; 2Hospital at Home, Fondation Santé Service ...
Postel-Vinay N, Shao JD, Pinton A, Servais A, Gebara N, Amar L   +5 more
doaj  

Blood pressure measurement using only a smartphone

npj Digital Medicine, 2022
Hypertension is an immense challenge in public health. As one of the most prevalent medical conditions worldwide, it is a major cause of premature death.
Lorenz Frey, Carlo Menon, Mohamed Elgendi   +2 more
doaj   +1 more source

Assessment of practical skill in measuring blood pressure in undergraduate nursing students [PDF]

, 2015
Background: Blood pressure is an important vital sign that reflects systemic and focal changes. Planning of treating most of the disease is based on the values obtained from this measurement.
Hamidreza, Sadeghi Gandomani, Masoume, Delaram, Mehdi, Jafari   +2 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Office blood pressure measurement: A comprehensive review

The Journal of Clinical Hypertension, 2021
The conventional auscultatory methods for measuring blood pressure have been used to screen, diagnose, and manage hypertension since long. However, these have been found to be prone to errors especially the white coat phenomena which cause falsely high ...
Saulat Siddique, Aamir Hameed Khan, Hunaina Shahab, Yu‐Qing Zhang, Jam Chin Tay, Peera Buranakitjaroen, Yuda Turana, Narsingh Verma, Chen‐Huan Chen, Hao‐Min Cheng, Tzung‐Dau Wang, Huynh Van Minh, Yook‐Chin Chia, Kazuomi Kario   +13 more
doaj   +1 more source

Accuracy of a New Wrist Cuff Oscillometric Blood Pressure Device: Comparisons with Intraarterial and Mercury Manometer Measurements [PDF]

, 2017
Accurate measurement of arterial blood pressure is of great importance for the diagnosis and treatment of hypertension. Because of the chronic nature of antihypertensive drug therapy, the involvement of the patient in blood pressure control is desirable.
Lüscher, T.F., Matteo, C. di, Meier, B., Watson, S., Wenzel, R.R.   +4 more
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