Results 221 to 230 of about 1,144,849 (350)

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim   +16 more
wiley   +1 more source

Repurposing space medical technology for perioperative and intensive care: a clinical proof-of-concept. [PDF]

open access: yesBr J Anaesth
Scarpa J   +5 more
europepmc   +1 more source

Fluorescent Polymeric Nanofibers as Ratiometric Multiplexed Skin Sensors of pH and Oxygen

open access: yesAdvanced Healthcare Materials, EarlyView.
Fluorescent polymeric nanofibers and nanorods are produced as ratiometric sensors of two important physiological parameters: pH and oxygen. They operate by dual Forster resonance energy transfer from large number of energy donor dyes to limited number of two distinct energy acceptors, enabling simultaneous sensing of pH and oxygen.
Rémi Pelletier   +2 more
wiley   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

open access: yesAdvanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji   +8 more
wiley   +1 more source

Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds

open access: yesAdvanced Healthcare Materials, EarlyView.
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar   +7 more
wiley   +1 more source

Development of a Customizable Web-Based Dashboard for Remote Blood Pressure Monitoring: Feasibility and Usability Implementation Study. [PDF]

open access: yesJMIR Form Res
Wollen J   +15 more
europepmc   +1 more source

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