Results 141 to 150 of about 12,332,569 (295)

Melt rate profiles of Bunyamwera S segment amplicons detected in blood-fed mosquitoes.

, 2015
Melt rate profiles of Bunyamwera S segment amplicons detected in blood-fed mosquitoes.
Laban Njoroge (778275), Jandouwe Villinger (377255), Yvonne Ukamaka Ajamma (778273), Daniel K. Masiga (307648), David Omondi (778272), Burtram C. Fielding (778274)   +5 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Ambulatory blood pressure monitoring profiles in Asia

The Journal of Clinical Hypertension
High blood pressure (BP) remains a major health problem globally, with a proportion of hypertension‐mediated organ damage (HMOD) increasing worldwide including in Asia region. Cardiovascular (CV), cerebral and kidney diseases related to hypertension were
Bambang Widyantoro, Jennifer M. Nailes, Apichard Sukonthasarn, Arieska Ann Soenarta, HOPE Asia Network   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Pan-disease blood protein profiles of rheumatic autoimmune diseases

Communications Medicine
Background Systemic autoimmune rheumatic diseases (SARDs) are a heterogeneous group of autoimmune conditions characterized by immune system dysregulation leading to chronic inflammation and tissue damage.
Josefin Kenrick, Charlotta Preger, María Bueno Álvez, Maria Alejandra Ulloa, Göran Bergström, Antonella Notarnicola, Begum Horuluoglu, Angeles S. Galindo-Feria, Anna Smed-Sörensen, Anna Färnert, Anna Norrby-Teglund, Iva Gunnarsson, Marie Wahren-Herlenius, Marie Holmqvist, Leonid Padyukov, Karine Chemin, Lina Marcela Diaz-Gallo, Ingrid E. Lundberg, Elisabet Svenungsson, Vivianne Malmström, Lars Klareskog, Sofia Bergström, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Elisa Pin   +25 more
doaj   +1 more source

The proposal to discontinue blood testing at the Munster Centre of the Irish Blood Transfusion Service Board (BTSB) - assessment by a representative regional group

, 1998
The role of the Irish Blood Transfusion Service is crucial to the operation of our health care system. In its 1965 Establishment Order, the key functions of the BTSB are described, inter alia, as follows (a) to take over the property {including chosen ...
Irish Blood Transfusion Service (IBTS)
core