Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Effects of BSFL on growing-finishing pigs in growth performance, nutrient digestibility, blood profiles, and gas emission. [PDF]
Chang S +7 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Blood Profiles in the Prediction of Radioiodine Refractory Papillary Thyroid Cancer: A Case-Control Study. [PDF]
Liu H +5 more
europepmc +1 more source
The Value of Chemical Screening Profiles on Blood
Chemical screening profiles on blood specimens are designed to yield information that may lead to new and additional clinical diagnoses, to revision of clinically established diagnoses, to confirmed impressions of the physician and to following the ...
Bakerman, Seymour
core
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Impact of varying levels of HepatoMax in drinking water on liver performance and blood profiles in broiler chickens. [PDF]
Behboodi HR +2 more
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Bioinformatics in Dentistry: Preoperative Healing Prediction Using Artificial Intelligence and Patient Blood Profiles in Electronic Health Records. [PDF]
Alturki AA, Bin Muammar AF.
europepmc +1 more source
Blood pressure and its correlates in children and adolescents in urban Nigeria [PDF]
Background: A substantial increase in the incidence of chronic non-communicable diseases (NCDs) and a decline in communicable diseases and poverty-related diseases are occurring in developing countries (including Nigeria) as a result of an ...
Ogboye, Oluwatoyin
core

