Results 201 to 210 of about 329,241 (267)

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Urine protein electrophoresis analysis in dogs with systemic inflammatory response syndrome. [PDF]

J Vet Intern Med
Jung R, Bae H, Cho KW, Park J, Yu DH.
europepmc   +1 more source

Ribonucleotides Amplify Mitochondrial DNA‐Driven cGAS–STING Activation via FdUMP‐ribonucleotide Hybrid Particles to Potentiate Chemoimmunotherapy

Advanced Science, EarlyView.
This work develops a metabolic sharing strategy that employs cytidine monophosphate (CMP) to competitively reprogram floxuridine (FUDR) pyrimidine metabolism in colorectal tumor cells. Elevated intracellular FdUMP induces nucleotide imbalance, drives mitochondrial DNA release and cGAS‐STING innate immune cascade activation, and potentiates robust ...
Chao Wang, Chenxuan Zhao, Yesong Yao, Zhiwen Zou, Anxin Shi, Zhuo Feng, Mingkang Yang, Yue Yu, Yang Liu, Xuehui Rui, Jinhui Wu   +10 more
wiley   +1 more source

The Hidden Link: Cryoglobulinemic Membranoproliferative Glomerulonephritis Secondary to Monoclonal Gammopathy of Renal Significance. [PDF]

J Med Cases
Mehyar S, Gomes A, Ghumman HK, Ghumman AK, Eweis N, Pishva S, Kenmoe J.   +6 more
europepmc   +1 more source

Acute Phase Proteins in Cats Naturally Infected or Seropositive for <i>Leishmania infantum</i>. [PDF]

Animals (Basel)
Spada E, Castelli G, Bruno F, Vitale F, Oliveri E, Di Pasquale ML, Biondi V, Migliazzo A, Perego R, Baggiani L, Koenhemsi L, Alan M, Or ME, Proverbio D.   +13 more
europepmc   +1 more source

An Unusual Case of Renal-Limited Giant Cell Arteritis. [PDF]

Cureus
Crowder S, Pant P, Madruga M, Carlan S.
europepmc   +1 more source

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Genetic Diversity and Divergence in Chinese Yak (Bos grunniens) Populations Inferred from Blood Protein Electrophoresis

Biochemical Genetics, 1997
Zhang Yaping, Y P Zhang
exaly