Results 1 to 10 of about 2,038,094 (307)

Analysis of HLA-Ⅰ antibody specificity and estimation of antigen immunogenicity: 96 patients recieved genotype-matched platelet transfusions

open access: yesZhongguo shuxue zazhi, 2022
Objective To analyze the specificity of HLA class-Ⅰ antibody in the patients received HLA-matched platelet transfusions and estimate the relative immunogenicity of HLA-Ⅰ antigens.
Ying LIU   +6 more
doaj   +1 more source

A case of McLeod syndrome caused by a nonsense variation c.942G>A in the XK gene: A case report

open access: yesFrontiers in Genetics, 2023
McLeod syndrome is a rare XK gene-related progressive, debilitating disease involving multiple systems. The blood group phenotypes in McLeod syndrome patients usually display the Kx antigen loss and a decrease in the Kell blood group system antigen ...
Yanling Ying   +12 more
doaj   +1 more source

The Significance of RHD Genotyping and Characteristic Analysis in Chinese RhD Variant Individuals

open access: yesFrontiers in Immunology, 2021
BackgroundRhD is the most important and complex blood group system because of its highly polymorphic and immunogenic nature. RhD variants can induce immune response by allogeneic transfusion, organ transplantation, and fetal immunity.
Yanling Ying   +11 more
doaj   +1 more source

Plasma metagenomics reveals regional variations of emerging and re-emerging pathogens in Chinese blood donors with an emphasis on human parvovirus B19

open access: yesOne Health, 2023
At present, many infectious pathogens, especially emerging/re-emerging pathogens, exist in the blood of voluntary blood donors and may be transmitted through blood transfusions.
Zhao Mengyi   +20 more
doaj   +1 more source

Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing

open access: yesFrontiers in Immunology, 2022
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang   +13 more
doaj   +1 more source

Human T-lymphotropic virus and transfusion safety. Does one size fit all? [PDF]

open access: yes, 2015
Human T-cell leukemia viruses (HTLV-1 and HTLV-2) are associated with a variety of human diseases, including some severe ones. Transfusion transmission of HTLV through cellular blood components is undeniable.
Catalano, Liviana   +7 more
core   +1 more source

Leucoreduction of blood components. an effective way to increase blood safety? [PDF]

open access: yes, 2015
Over the past 30 years, it has been demonstrated that removal of white blood cells from blood components is effective in preventing some adverse reactions such as febrile non-haemolytic transfusion reactions, immunisation against human leucocyte antigens
Bianchi, Maria   +6 more
core   +1 more source

High-Resolution Analysis Identifies High Frequency of KIR-A Haplotypes and Inhibitory Interactions of KIR With HLA Class I in Zhejiang Han

open access: yesFrontiers in Immunology, 2021
Killer cell immunoglobulin-like receptors (KIR) interact with human leukocyte antigen (HLA) class I molecules, modulating critical NK cell functions in the maintenance of human health.
Sudan Tao   +6 more
doaj   +1 more source

Microstructured Thin Film Nitinol for a Neurovascular Flow-Diverter [PDF]

open access: yes, 2016
A cerebral aneurysm occurs as a result of a weakened blood vessel, which allows blood to flow into a sac or a ballooned section. Recent advancement shows that a new device, ‘flow-diverter’, can divert blood flow away from the aneurysm sac.
Chen, Yanfei   +5 more
core   +2 more sources

Impact of injection buffer volume to perform bronchoalveolar lavage fluid collection for isolating alveolar macrophages to investigate fine particle-induced IL-1α secretion

open access: yesJournal of Immunotoxicology, 2021
The importance of alveolar macrophages has been reported in many toxicology/immunology studies. Alveolar macrophages release interleukin (IL)-1α as a damage-associated molecular pattern (DAMP) when stimulated by fine particles.
Eita Sasaki   +4 more
doaj   +1 more source

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