Results 21 to 30 of about 252,906 (261)

The plasma separation card as a novel solution for enhancing central laboratory capability for HIV-1 viral load monitoring in limited-access settings.

PLOS Global Public Health, 2023
Measurement of HIV-1 viral load (VL) is essential for monitoring antiretroviral treatment (ART) efficacy. The preferred specimen type for VL is plasma, but in remote settings where collection and preservation of plasma many not be possible, dried blood ...
Charles Kiyaga, Caroline Makoha, Ivan Nkugwa, Christopher Okiira, Richard Okwir, Sirak Zenebe Gebreab, Patricia Rodriguez-Ventosa Suarez, Benjamin LaBrot, Ana Carrasco Durán   +8 more
doaj   +1 more source

Blood specimen rejection rate in clinical laboratory: A systematic review and meta-analysis

Practical Laboratory Medicine, 2023
Background: Clinical laboratory errors have a great impact on patient safety and treatment. Although specimen rejections result in longer turnaround times and increased health-care costs, different studies present inconsistent findings.
Solomon Getawa, Melak Aynalem, Mulugeta Melku, Tiruneh Adane   +3 more
doaj   +1 more source

When to collect blood specimens: midmorning vs fasting samples [PDF]

Clinical Chemistry, 1998
Abstract This study was carried out to define the consequences of collecting blood specimens during the forenoon instead of using fasting specimens collected early in the morning. Extensive laboratory data were obtained from specimens collected from fasting participants at 0800, after breakfast at 0930, and again at 1100.
E, Leppänen, B, Dugué
openaire   +2 more sources

Benzene Derivatives from Ink Lead to False Positive Results in Neonatal Hyperphenylalaninemia Screening with Ninhydrin Fluorometric Method

International Journal of Neonatal Screening, 2020
Ninhydrin-based fluorometric quantification of phenylalanine is one of the most widely used methods for hyperphenylalaninemia (HPA) screening in neonates due to its high sensitivity, high accuracy, and low cost.
Shuren Feng, Joanne Mei, Lu Yang, Ping Luo, Xiaonan Wang, Yuan Wang, Jingyi Yao, Lan Cui, Lei Pan, Zefang Wang, Li Xin   +10 more
doaj   +1 more source

Factors affecting autologous peripheral blood hematopoietic stem cell collections by large-volume leukapheresis: a single center experience [PDF]

Einstein (São Paulo), 2011
Objective: To evaluate factors affecting peripheral bloodhematopoietic stem cell yield in patients undergoing large-volumeleukapheresis for autologous peripheral blood stem cell collection.Methods: Data from 304 consecutive autologous peripheral ...
Araci Massami Sakashita, Andrea Tiemi Kondo, Andreza Alice Feitosa Ribeiro, Andrea Neri Folchini Cipolletta, Monica Vilela Colesanti, Nelson Hamerschlak, Jose Mauro Kutner   +6 more
doaj   +4 more sources

SPIDIA-RNA: second external quality assessment for the pre-analytical phase of blood samples used for RNA based analyses. [PDF]

PLoS ONE, 2014
One purpose of the EC funded project, SPIDIA, is to develop evidence-based quality guidelines for the pre-analytical handling of blood samples for RNA molecular testing.
Francesca Malentacchi, Mario Pazzagli, Lisa Simi, Claudio Orlando, Ralf Wyrich, Kalle Günther, Paolo Verderio, Sara Pizzamiglio, Chiara Maura Ciniselli, Hui Zhang, Vlasta Korenková, Lynne Rainen, Tzachi Bar, Mikael Kubista, Stefania Gelmini   +14 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Consistency in the Assessment of Dried Blood Spot Specimen Size and Quality in U.K. Newborn Screening Laboratories

International Journal of Neonatal Screening
In 2015, U.K. newborn screening (NBS) laboratory guidelines were introduced to standardize dried blood spot (DBS) specimen quality acceptance and specify a minimum acceptable DBS diameter of ≥7 mm. The UK ‘acceptable’ avoidable repeat rate (AVRR) is ≤2%.
Stuart J. Moat, James R. Bonham, Christine Cavanagh, Margaret Birch, Caroline Griffith, Lynette Shakespeare, Clare Le Masurier, Claire Manfredonia, Beverly Hird, Philippa Goddard, Sarah Smith, Laura Wainwright, Rachel S. Carling, Jennifer Cundick, Fiona Jenkinson, Catherine Collingwood, Nick Flynn, Nazia Taj, Mehdi Mirzazadeh, Tejswurree Ramgoolam, Liz Robinson, Amy Headley, Tessa Morgan, David Elliman, Lesley Tetlow   +24 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Willingness to Use Home Collection Methods to Provide Specimens for SARS-CoV-2/COVID-19 Research: Survey Study

Journal of Medical Internet Research, 2020
BackgroundInnovative laboratory testing approaches for SARS-CoV-2 infection and immune response are needed to conduct research to establish estimates of prevalence and incidence.
Hall, Eric William, Luisi, Nicole, Zlotorzynska, Maria, Wilde, Gretchen, Sullivan, Patrick, Sanchez, Travis, Bradley, Heather, Siegler, Aaron J   +7 more
doaj   +1 more source