Results 191 to 200 of about 5,469,182 (343)
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Soyfood Consumption Patterns: Effects of Product Attributes and Household Characteristics [PDF]
Effects of perceived attributes of soyfoods on the consumption patterns for six different soyfood products are evaluated. Perceived attributes include convenience, health benefits, and taste.
Balasubramanian, Siva K. +2 more
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
ASSESSMENT OF NEWLY DEVELOPED PERFLUOROCARBON EMULSION: OXYGEN CARRYING CAPACITY AS THE BLOOD SUBSTITUTE IN VIVO [PDF]
, 2001 Jun Sakanoue +5 more
openalex +1 more source
Salt substitution to lower population blood pressure [PDF]
, 2020 Feng J. He +3 more
openalex +1 more source
Aerospace Medicine and Biology: A continuing bibliography, supplement 191 [PDF]
A bibliographical list of 182 reports, articles, and other documents introduced into the NASA scientific and technical information system in February 1979 is ...
core +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
The efficacy of a low-sodium salt substitute enriched with potassium to improve sodium-to-potassium ratio and reduce blood pressure in adolescents and their families in Soweto, South Africa: study protocol for randomised controlled trial [PDF]
Simone H. Crouch +3 more
openalex +1 more source