Results 81 to 90 of about 2,385,893 (283)
How Nitric Oxide Hindered the Search for Hemoglobin-Based Oxygen Carriers as Human Blood Substitutes. [PDF]
Samaja M, Malavalli A, Vandegriff KD.
europepmc +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Hemoglobin Based Blood Substitutes: Increased Morbidity and Mortality
Includes descriptive metadata provided by producer in MP3 file: "Surgery ICU Rounds - Podcasts - Hemoglobin Based Blood Substitutes: Increased Morbidity and Mortality."In this week's Journal of the American Medical Association a meta-analysis was ...
Guy, Jeffrey S.
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Investigation on the Decomposition of Sugar Substitutes in Simulated Blood
In recent years several arguments have been raised as to whether sugar substitutes help or harm us. This SIR investigation is focused on researching the effects of sugar substitutes in simulated blood.
Krishnan, Priyankka
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New Artificial Blood Substitutes using Fluorinated Ionic Liquids [PDF]
"In the past decades, safe and effective artificial oxygen carriers (AOC), also named as “blood substitutes”, have been proposed and extensively studied in chemistry and medical science.
Ferreira, Margarida Lourenço
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Issued by the National Blood Users Group
Rapid and continuing loss of blood is life-threatening. Ensuring that tissue oxygenation is maintained at a level consistent with avoidance of critical ischaemic organ damage and irreversible organ failure demands speed and skill.
National Blood Users Group
core
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A guideline for transfusion of red blood cells in surgical patients
Blood transfusion carries a real but unquantifiable risk of adverse outcome in surgical patients from infectious, immunological and cardiorespiratory morbid events.
National Blood Users Group
core

