Results 91 to 100 of about 21,882 (168)

Organ Transplantation: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 1, January 2026.
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley   +1 more source

Dextran vs. Crystalloid Priming Solution in Cardiac Surgery: A Randomized Trial on Acute Kidney Injury

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 1, January 2026.
ABSTRACT Background Acute kidney injury (AKI) is a frequent complication following cardiac surgery involving cardiopulmonary bypass (CPB). This is partly attributable to crystalloid‐based priming solutions causing both hemolysis and loss of oncotic pressure with tissue edema. While colloids like albumin and starches have not shown clear benefits, pilot
Oskar Juvakka, Andreas Wallinder, Peter Hasse Møller‐Sørensen, Klaus Matschke, Anders Jeppsson, Lukas Lannemyr   +5 more
wiley   +1 more source

Transoperative refusion: a simple and safe method in emergency surgery

Revista do Colégio Brasileiro de Cirurgiões
The objective is to reinforce the importance of blood reinfusion as a cheap, safe and simple method, which can be used in small hospitals, especially those in which there is no blood bank.
Luiz Carlos Buarque Gusmão, Sérgio Henrique Chagas Valoes, José da Silva Leitão Neto   +2 more
doaj   +1 more source

The effect of stored autologous blood transfusion on IL-1, IL-6, TNF-α and liver function recovery in patients undergoing liver cancer surgery

Discover Oncology
Purpose This study aim is to evaluate the application of stored autologous blood transfusion in liver cancer surgery and explore its impact on postoperative changes in inflammatory factors and liver function recovery.
Dongliang Yin, Ruirong Niu, Peilin Lu, Ruilong Yin, Zhiqiang Lin   +4 more
doaj   +1 more source

Role of Frailty in Assessing Eligibility for CAR T‐Cell Therapy in Haematology

European Journal of Haematology, Volume 116, Issue 1, Page 4-13, January 2026.
ABSTRACT Background and Objectives Frailty is a key consideration in determining whether a patient is robust enough for CAR T‐cell therapy; however, it should not represent a barrier to treatment. Our study aimed to describe the extent of research concerning frailty in haematology adult and paediatric patients being considered for CAR T‐cell therapy ...
Jennifer Clesham, Joan McGrory, Aoife Bannon, Deirbhle Cox, Maura Dowling   +4 more
wiley   +1 more source

Impact of Anemia on Outcomes Following Total Hip Replacement Surgery and Patient Prognosis

Orthopaedic Surgery, Volume 18, Issue 1, Page 3-15, January 2026.
The processes involved in iron acquisition are closely controlled by hepcidin‐based regulatory mechanisms. Hepcidin is a peptide hormone mainly produced in the liver, acting as an acute‐phase reactant that responds to changes in plasma iron levels. It does this by binding to ferroportin, a protein responsible for exporting iron from cells, leading to ...
Zhihong Hu, Xuejia Zhao, Zhang Chen
wiley   +1 more source

Chimeric Antigen Receptor T‐Cell Therapy: More Than an Anti‐Cancer Drug

HLA, Volume 107, Issue 1, January 2026.
ABSTRACT Initially, chimeric antigen receptor (CAR) T‐cell therapy was developed to eliminate malignant B cells in haematological B‐cell malignancies by targeting CD19 and B‐cell maturation antigen. This approach achieved notable success, resulting in (malignant) B‐cell depletion and inducing clinical remission in cancer patients.
Hannah C. M. Schenk, Ilse Gille, Carolt Arana, Jordi Rovira, Eduard Palou, Fritz Diekmann, Dave L. Roelen, Mirjam H. M. Heemskerk, Sebastiaan Heidt   +8 more
wiley   +1 more source

Primary Hepatic Hemangiosarcoma With Hemoperitoneum in a Dog: Clinical Course and Therapeutic Outcome

Case Reports in Veterinary Medicine, Volume 2026, Issue 1, 2026.
A 14‐year‐old neutered male mixed‐breed dog presented with hemoperitoneum secondary to rupture of a primary hepatic mass. Following stabilization with whole blood transfusion, a hepatic lobectomy was performed. Histopathological examination and CD31 immunolabeling confirmed a diagnosis of hemangiosarcoma.
Myeong-Yeon Lee, Jong-Hyun Moon, Jinsu Mok, Dowoo Lim, Ju-Yeong Kim, Seo-Yeong Jung, Eunbin Jeong, Hyomi Jang, Dong-In Jung, Iosif Vasiu   +9 more
wiley   +1 more source

High Concentrations of β2‐Microglobulin Do Not Inhibit In Vitro Generation of Functional Dendritic Cells

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
β2‐microglobulin (β2M) is a small protein playing a critical role in stabilizing major histocompatibility complex class I (MHC‐I) molecules on nucleated cells. Elevated levels of β2M have been observed in several cancers, inflammatory and autoimmune conditions, and renal failures.
Pavla Taborska, Dmitry Stakheev, Katerina Krausova, Jirina Bartunkova, Daniel Smrz, Poorani Gurumallesh   +5 more
wiley   +1 more source

Effects of intraoperative cell salvage versus preoperative autologous blood donation on postoperative coagulation in cardiac surgery. [PDF]

Am J Transl Res
Liu J, Zhang H, Guo F, Wang F, Cui R, Pan X, Zhang X.   +6 more
europepmc   +1 more source