Results 61 to 70 of about 229,903 (214)

Alternatives to blood transfusion

The Lancet, 2013
The use of alternatives to allogeneic blood continues to rest on the principles that blood transfusions have inherent risks, associated costs, and affect the blood inventory available for health-care delivery. Increasing evidence exists of a fall in the use of blood because of associated costs and adverse outcomes, and suggests that the challenge for ...
Spahn, Donat R, Goodnough, Lawrence T
openaire   +3 more sources

Neonatal alloimmune thrombocytopenia caused by anti-HPA antibodies in pregnant Chinese women: a study protocol for a multicentre, prospective cohort trial

BMC Pregnancy and Childbirth, 2017
Background Neonatal alloimmune thrombocytopenia (NAIT), caused by maternal antibodies raised against alloantigens carried on foetal platelets, is a very common haematological abnormality in newborns worldwide.
Li Chen, Zhiwei Liu, Tiemei Liu, Xianjun Ma, Meiying Rao, Yongjun Wang, Bo Sun, Wen Yin, Jun Zhang, Beizhan Yan, Xiaojuan Li, Qiushi Wang, Lei Zhang, Jun Wen, Fenghua Liu, Peng Wang, Yaming Wei, Yuanshuai Huang, Jiang Wu, Yi Guo, Yinlan Kang, Xiaochuan Song, Xiangfu Liu, Genling Zhang, Tingting Xie, Yonggeng Chen, Xiaojing Zeng, Zhongjun Li   +27 more
doaj   +1 more source

Hepcidin gene polymorphisms and iron overload in β-thalassemia major patients refractory to iron chelating therapy

BMC Medical Genetics, 2020
Background β Thalassemia is one of the most common groups of hereditary haemoglobinopathies. Affected people with thalassemia major are dependent on regular blood transfusion which on the long term leads to iron overload.
Parinaz Zarghamian, Azita Azarkeivan, Ali Arabkhazaeli, Ahmad Mardani, Majid Shahabi   +4 more
doaj   +1 more source

A Novel Alternating Joint Longitudinal Model for Post-ICU Hemoglobin Prediction [PDF]

arXiv, 2023
Anemia is common in patients post-ICU discharge. However, which patients will develop or recover from anemia remains unclear. Prediction of anemia in this population is complicated by hospital readmissions, which can have substantial impacts on hemoglobin levels due to surgery, blood transfusions, or being a proxy for severe illness.
arxiv  

Hemin regulates platelet clearance in hemolytic disease by binding to GPIbα

Platelets
Hemolysis is associated with thrombosis and vascular dysfunction, which are the pathological components of many diseases. Hemolytic products, including hemoglobin and hemin, activate platelets (PLT).
Man Zhao, Dongxin Peng, Yuxuan Li, Minwei He, Yulong Zhang, Qianqian Zhou, Sujing Sun, Ping Ma, Liping Lv, Xiaohui Wang, Linsheng Zhan   +10 more
doaj   +1 more source

Transfusion of stored autologous blood in patients with low-grade pseudomyxoma peritonei: A retrospective analysis of its safety and outcome

Frontiers in Oncology, 2022
BackgroundPseudomyxoma peritonei is a rare disease that presents as a malignant tumor on the peritoneal surface. Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy is the standard treatment for this disease and frequently ...
Xiaoyun Gao, Liduo Kou, Hang Guan, Hua Tian, Junhui Jia, Yu Bai, Wei Bai, Yanhui Di, Ruiqing Ma, Xinhua Wang   +9 more
doaj   +1 more source

Clinical experience with ferric carboxymaltose in the management of anemia in acute gastrointestinal bleeding [PDF]

, 2019
Objective The aim of this study was to assess the efficacy and safety of intravenous ferric carboxymaltose (FCM) following hospitalization for acute gastrointestinal bleeding (AGIB) in the context of a restrictive transfusion strategy.
Ballester-Clau, Raquel, Cucala-Ramos, Mercedes, López-Barroso, Laura, Planella de Rubinat, Montse, Reñé Espinet, Josep Maria, Torres Vicente, Gisela, Voltà-Pardo, Tania   +6 more
core   +2 more sources

Sorcin regulate pyroptosis by interacting with NLRP3 inflammasomes to facilitate the progression of hepatocellular carcinoma

Cell Death and Disease, 2023
A high recurrence rate and easy metastasis are two prominent clinical features of hepatocellular carcinoma (HCC), which is also the most common cause of cancer-related death. However, the molecular pathogenesis of HCC remains unclear.
Zhenfen Li, Ziyue Yang, Yuanyuan Zhu, Chunmeng Fu, Ning Li, Fang Peng   +5 more
doaj   +1 more source

Correlation between type Ⅱ CD36 deficiency and intron polymorphism

Zhongguo shuxue zazhi, 2022
Objective To study the correlation between type ⅡCD36 deficiency and the polymorphism of intron sequence. Methods A total of 516 random healthy platelet donors from Liaoning Blood Center were involved: 241 of them were tested for CD36 antigen and CD36 ...
Fengqiu LIN, Xiaofeng LI, Jianping LI
doaj   +1 more source

Hemolytic diseases of the fetus and newborn caused by anti-Dib: a case report and related research

Zhongguo shuxue zazhi
Objective To identify the specificity of alloantibody against high-frequency antigens in one case suffering with severe hemolytic diseases of the fetus and newborn (HDFN) and to screen for matching blood for transfusion.
Zhijian LIAO, Shuangshuang JIA, Jizhi WEN, Chunyan MO, Yuan SHAO, Runqing ZHANG, Guangping LUO, Yanli JI   +7 more
doaj   +1 more source