Results 81 to 90 of about 966,913 (304)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

Fasting plasma glucose level and in-hospital cardiac arrest in patients with acute coronary syndrome: findings from the CCC-ACS project

Annals of Medicine
Background The prognosis of patients with coronary artery disease is adversely affected by elevated fasting plasma glucose (FPG) levels. However, the relationship between FPG levels and in-hospital cardiac arrest (IHCA) remains unclear.Objectives The ...
Kangning Han, Xia Li, Mengmeng Li, Tong Liu, Fang Liu, Jie Yang, Shuyu Jin, Jing Liu, Jun Liu, Yongchen Hao, Jing Lin, Chenxi Jiang, Ribo Tang, Jianzeng Dong, Dong Zhao, Deyong Long, Changsheng Ma   +16 more
doaj   +1 more source

Flow dynamics control the effect of sphingosine-1-phosphate on endothelial permeability in a microfluidic vessel bifurcation model [PDF]

, 2018
Blood vessels are lined by endothelial cells that form a semipermeable barrier to restrict fluid flow across the vessel wall. The endothelial barrier is known to respond to various molecular mechanisms, but the effects of mechanical signals that arise ...
Spychalski, Griffin
core  

The Blood Vessels of the Skin

Journal of Investigative Dermatology, 1976
During the last 25 years, cutaneous biologists have been particularly interested in abnormal cutaneous vascular patterns, the profusion of capillary anastomoses, the leakiness of venules, clotting, fibrinolysis, and blood viscosity. As a result, the effects of hypoxia and the factors that encourage new vessel proliferation are better understood than ...
openaire   +2 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Evaluation of non-dilated left ventricular cardiomyopathy patients with reduced and preserved left ventricular ejection fraction using cardiac magnetic resonance feature tracking technology

BMC Cardiovascular Disorders
Background To investigate the diagnostic value of cardiac magnetic resonance imaging feature tracking (CMR-FT) in evaluating patients with non-dilated left ventricular cardiomyopathy (NDLVC) and either reduced or preserved left ventricular ejection ...
Chunlong Yan, Shuang Li, Baiyan Zhuang, Shujuan Yang, Jiayi Liu, Lei Xu   +5 more
doaj   +1 more source

Generalized hybrid coronary revascularization vs. conventional off-pump coronary artery bypass grafting for multivessel coronary artery disease

Frontiers in Cardiovascular Medicine
BackgroundHybrid coronary revascularization (HCR) has been demonstrated as a safe and effective revascularization strategy in selected patients with multivessel coronary artery disease; however, the inclusion criteria are too strict.ObjectivesThis study ...
Shuai Zhang, Shuai Zhang, Ping Li, Ping Li, Guang Li, Guang Li, Yunfeng Yan, Yunfeng Yan, Tao Sun, Tao Sun, Ji Lin, Ji Lin, Chenhao Zhang, Shuo Liu, Shuo Liu, Zheng Qu, Zheng Qu, Bin You, Bin You   +18 more
doaj   +1 more source

The dispersion and dissipation of waves in blood vessels [PDF]

Dispersion and dissipation of waves in blood ...
Anliker, M., Maxwell, J. A.
core   +1 more source

Particle based modeling and simulation of the red blood cell Infected by malaria-mechanism of the margination of the Infected red blood cell [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011), Imai, Y, Ishikawa, T, Yamaguchi, T   +3 more
core