Results 51 to 60 of about 13,333 (225)

Sickle Cell Disease: Historical Overview and Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

Experimental implantation of an arterial substitute made of silicone reinforced with polyester fabric in rabbits

open access: yesClinics
OBJECTIVES: The aim of this study was to analyze silicone tubes with an internal diameter of 4 mm as a possible material for vascular prostheses. METHODS: Grafts were implanted into the infrarenal aortas of 33 rabbits.
Laila Massad Ribas   +5 more
doaj   +1 more source

Vascular access cannulation in hemodialysis patients: technical approach

open access: yesBrazilian Journal of Nephrology, 2019
Introduction: The vascular access cannulation technique varies among clinics, and guidelines on vascular access give little importance to cannulation techniques. The objective of this study was to evaluate the cannulation technique and to determine which
Manuel Carlos Martins Castro   +5 more
doaj   +2 more sources

Characteristics, properties and limitations of per‐ or polyfluoroalkyl substances (PFASs) and fluoropolymers

open access: yesPolymer International, EarlyView.
An overview and categorization of man‐made per‐ or polyfluoroalkyl substances (PFASs) including low‐molar‐mass and high‐molar‐mass fluorochemicals, and their international regulations is presented. Though certain PFASs are toxic, bioaccumulative and cross the human cellular membranes, others, such as fluoropolymers, are safe, reliable and involved in ...
Bruno Améduri
wiley   +1 more source

Surgical repair of an aortoesophageal fistula after salvage thoracic endovascular aortic repair: a case report

open access: yesJournal of Medical Case Reports
Background An aortoesophageal fistula can prove to be fatal. Salvage thoracic endovascular aortic repair as a bridging therapy and radical surgery with thoracotomy should be considered while treating aortoesophageal fistula without spontaneous closure ...
Hisashi Uemura   +7 more
doaj   +1 more source

Proximal endovascular blood flow shunt for thoracoabdominal aortic aneurism without total aortic clamping

open access: yesRevista do Colégio Brasileiro de Cirurgiões
The authors present a surgical approach to type III and IV Crawford aneurysms that does not need total aortic clamping, which allows the more objective prevention of direct ischemic damage, as well as its exclusion by the endoprosthesis implantation ...
Gaudencio Espinosa   +6 more
doaj   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

open access: yesSmart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang   +8 more
wiley   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

open access: yesVIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro   +6 more
wiley   +1 more source

Infected Paravisceral Aneurysm Repair with Parallel Stent Grafts

open access: yesVascular Specialist International
An infected aortic aneurysm (IAA) is a rare but potentially life-threatening pathology characterized by rapid growth and a substantial risk of rupture compared to non-infected aneurysms.
Iria Fernández Álvarez   +3 more
doaj   +1 more source

Complex biomechanical study of chitosan microtubes

open access: yesRussian Open Medical Journal, 2019
Mechanical parameters of a biotransplant made of the aminopolysaccharide chitosan were estimated in an in vitro experiment. Using the values obtained, finite element simulation of the "arterial vessel-microtube" system was carried out. As a result of our
Natalia O. Gegel   +4 more
doaj   +1 more source

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