Results 211 to 220 of about 1,235,836 (377)

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq   +4 more
wiley   +1 more source

Monocyte-Derived cxcl12 Guides a Directional Migration of Blood Vessels in Zebrafish. [PDF]

open access: yesArterioscler Thromb Vasc Biol
Lu X   +5 more
europepmc   +1 more source

Organoid‐Like Neurovascular Spheroids Promote the Recovery of Hypoxic‐Ischemic Skin Flaps Through the Activation of Autophagy

open access: yesAdvanced Healthcare Materials, EarlyView.
Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie   +5 more
wiley   +1 more source

Prevalence of cardiovascular risk factors in persons with venous thromboembolism aged 50 years or younger

open access: yesBlood Vessels, Thrombosis & Hemostasis
: The risk of cardiovascular disease (CVD) is elevated in individuals with a history of venous thromboembolism (VTE). It is uncertain whether younger patients, aged ≤50 years, have an increased prevalence of potentially modifiable CVD risk factors, which
Eng Soo Yap   +3 more
doaj  

Fundamental Difference in the Reactivity of the Blood Vessels in Skin Compared with those in Muscle [PDF]

open access: bronze, 1953
John T. Lanier   +4 more
openalex   +1 more source

Tri‐Layered Bioactive Cutaneous Scaffold with Integrated Bioactive Metal Organic Frameworks to Promote Full‐Thickness Infected Diabetic Wound Healing: Multifaceted Therapeutic Strategies

open access: yesAdvanced Healthcare Materials, EarlyView.
The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba   +8 more
wiley   +1 more source

A NOTCH4 intron 28 regulatory element controls arterial specification and lymphoid development from hPSCs

open access: yesBlood Vessels, Thrombosis & Hemostasis
: NOTCH signaling plays a critical role in arterial specification, and the formation of transient definitive lymphomyeloid progenitors and hematopoietic stem cells from hemogenic endothelium (HE).
Ho Sun Jung   +3 more
doaj  

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