Results 161 to 170 of about 1,413,486 (294)

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community: the MESA Lung study. [PDF]

Thorax
Hermann EA, Motahari A, Hoffman EA, Sun Y, Allen N, Angelini ED, Bertoni AG, Bluemke DA, Gerard SE, Guo J, Kaczka DW, Laine A, Michos E, Nagpal P, Pankow JS, Sack CS, Smith B, Stukovsky KH, Watson KE, Wysoczanski A, Barr RG.   +20 more
europepmc   +1 more source

The determination of the blood volume in man by the carbon monoxide and dye methods [PDF]

, 1949
F. C. Courtice, R. W. Gunton
openalex   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Absolute blood volume and long-term survival in chronic hemodialysis patients. [PDF]

Int J Artif Organs
Kron J, Broszeit S, Leimbach T, Kron S.
europepmc   +1 more source

THE IMMUNOPHYSIOLOGY OF TRICHINOSIS. ALTERATIONS IN THE BLOOD VOLUME AND THE THIOCYANATE SPACE IN RELATION TO THE DEVELOPMENT OF HUMORAL ANTIBODIES IN THE RABBIT 1 [PDF]

, 1951
Jerry K. Aikawa, George T. Harrell, Treva B. Miller   +2 more
openalex   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

The Significance of Relative Cerebral Blood Volume Index in Discriminating Glial Tumors from Brain Metastasis Using Perfusion Magnetic Resonance Imaging. [PDF]

Diagnostics (Basel)
Parlak AE, Yangoz B.
europepmc   +1 more source

BLOOD VOLUME PRECEDING AND FOLLOWING SPLENECTOMY IN HEMOLYTIC ICTERUS AND SPLENIC ANEMIA 1 [PDF]

, 1929
Herbert Z. Giffin, G. E. Brown, Grace M. Roth   +2 more
openalex   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source