QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda +8 more
wiley +1 more source
Influence of plant spacing and deblossoming on agromorphological and physiological traits of zombi pea. [PDF]
Priyadarsini S +6 more
europepmc +1 more source
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang +7 more
wiley +1 more source
Effects of banana blossom supplementation on metabolic parameters in prediabetic adults: a double-blind randomized clinical trial. [PDF]
Chotiprakornkul N +6 more
europepmc +1 more source
Electronic Structure Reorganization in MPS3 via d‐Shell‐Selective Alkali Metal Doping
Alkali metal doping of layered MPS3 antiferromagnets reveals d‐shell‐selective responses. While MnPS3 resists charge transfer due to its half‐filled 3d5 shell, FePS3 and NiPS3 behave similarly to CoPS3 by accommodating extra d‐electrons. Yet only CoPS3, with its least stable d‐shell, undergoes pronounced band restructuring and a semiconducting‐to ...
Jonah Elias Nitschke +12 more
wiley +1 more source
OrchardQuant-3D: combining drone and LiDAR to perform scalable 3D phenotyping for characterising key canopy and floral traits in fruit orchards. [PDF]
Xia Y +13 more
europepmc +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Volatile Compounds Profiling of Fresh <i>R. alba</i> L. Blossom by Headspace-Solid Phase Microextraction and Gas Chromatography. [PDF]
Antonova-Nedeltcheva D +3 more
europepmc +1 more source

