Results 61 to 70 of about 136,680 (289)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
BackgroundThe in vitro and in vivo anti-inflammatory and anti-oxidative effects of an amino acid (AA) blend (tryptophan, threonine, and methionine) in pigs.ObjectiveThis study aimed to evaluate the in vitro anti-inflammatory and anti-oxidative effects of
Sehyeong Ham +7 more
doaj +1 more source
Boston University Percussion Ensemble: Blossom and Bell, March 21, 2016 [PDF]
This is the concert program of the Boston University Percussion Ensemble: Blossom and Bell performance on Monday, March 21, 2016 at 8:00 p.m., at the Concert Hall, 855 Commonwealth Avenue.
School of Music, Boston University
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Belief Propagation for Linear Programming
Belief Propagation (BP) is a popular, distributed heuristic for performing MAP computations in Graphical Models. BP can be interpreted, from a variational perspective, as minimizing the Bethe Free Energy (BFE).
Chertkov, Michael +2 more
core +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock +4 more
wiley +1 more source
rTMS Combined with Mindfulness-Based Intervention for Anxiety Symptoms of Depression
Cheng-Ruey Joua +2 more
doaj +1 more source
Efficient Photolysis of Multidrug‐Resistant Polymicrobial Biofilms
Chronic wounds are prone to infections with multidrug‐resistant bacteria, forming polymicrobial biofilms that limit treatment options and increase the risk of severe complications.
Yongli Li +5 more
doaj +1 more source

