Results 101 to 110 of about 50,923 (254)

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

open access: yesAdvanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li   +8 more
wiley   +1 more source

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

open access: yesAdvanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo   +17 more
wiley   +1 more source

The Blow-Up of the Local Energy Solution to the Wave Equation with a Nontrivial Boundary Condition

open access: yesMathematics
In this study, we examine the wave equation with a nontrivial boundary condition. The main target of this study is to prove the local-in-time existence and the blow-up in finite time of the energy solution.
Yulong Liu
doaj   +1 more source

Scalable MoS2/Si Photodiode Arrays From Roll‐to‐Roll Mechanical Exfoliation

open access: yesAdvanced Science, EarlyView.
A dry roll‐to‐roll route transforms mechanically exfoliated MoS2 flake networks into silicon‐integrated photodiode arrays. The MoS2/Si junctions generate photovoltaic output without applied bias, allowing illuminated pixels to locate light spots and reconstruct simple images.
Yigit Sozen   +2 more
wiley   +1 more source

Blow up of solutions to ordinary differential equations arising in nonlinear dispersive problems

open access: yesElectronic Journal of Differential Equations, 2018
We study a new class of ordinary differential equations with blow up solutions. Necessary and sufficient conditions for finite blow up time are proved.
Milena Dimova   +2 more
doaj  

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

open access: yesAdvanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie   +10 more
wiley   +1 more source

Properties of a Parabolic System with Memory boundary Condition

open access: yes四川大学学报. 自然科学版, 2016
We study the blow-up for a parabolic system with a nonlinear memory boundary condition. By using the super-sub solution method and the integration technique, we obtain the complete classification for finite time blow-up and global existence.
LI Hui-fang, PANG Feng-qin, Wang Yu-Lan
doaj  

Stability of PEA2PbBr4 Thin‐Film Photodetectors under Thermal and Moisture Stress

open access: yesAdvanced Electronic Materials, EarlyView.
This study investigates the environmental durability of 2D perovskite photodetectors under extreme heat and humidity. While pristine films degrade in harsh environmental conditions, adding a halogen‐bonding agent significantly improves stability. This passivated device maintains stable performance in conditions mimicking space and solar applications ...
Sara Cepić   +3 more
wiley   +1 more source

Ultrathin, Fully Solution‐Processed P(VDF‐TrFE) Piezoelectric Sensor Matrix for Electronic Skin

open access: yesAdvanced Electronic Materials, EarlyView.
An ultrathin, fully solution‐processed 4×$\times$4 piezoelectric sensor array is developed for skinconformal electronicskin applications. The device integrates inkjetprinted polymer electrodes with a 226 nm P(VDFTrFE) active layer on a 4.53 μm$\umu{\rm m}$ Parylene C substrate, enabling extreme flexibility and robust tactile sensing. The array exhibits
Ninja Kajas   +4 more
wiley   +1 more source

Nonlinear convection in reaction-diffusion equations under dynamical boundary conditions

open access: yesElectronic Journal of Differential Equations, 2013
We study the blow-up phenomena for positive solutions of nonlinear reaction-diffusion equations including a nonlinear convection term $partial_t u = Delta u - g(u) cdot abla u + f(u)$ in a bounded domain of $mathbb{R}^N$ under the dissipative ...
Gaelle Pincet Mailly   +1 more
doaj  

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