Results 101 to 110 of about 102,014 (306)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Water Modeling Study on Interaction of Jet and 180 t Converter Bath with Bottom Blowing as well as Top and Bottom Combined Blowing

open access: yesTeshugang, 2015
According to the actual production situation of an 180 t converter, based on revised Froude number as experiment similarity number, a water model with geometrical-similar ratio 10 : 1 is established, the four holes symmetric bottom blowing test has been ...
包丽明, 吕国成, 刘坤
doaj  

Tailored Organogel Systems for Optimized Pesticide Delivery: Mechanistic Insights and Agricultural Applications

open access: yesAdvanced Science, EarlyView.
Utilizing molecular engineering for network design, three pesticide‐loaded organogels (PLOs) carriers exhibiting varying degrees of flexibility were prepared. The mechanical properties of these carriers, tunable via their network molecular structures, enhance their structural adaptability and retention stability at biological interfaces, thereby ...
Yue Wang   +6 more
wiley   +1 more source

Comparative study of heat transfer and pressure drop during flow boiling and flow condensation in minichannels [PDF]

open access: yes, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014)   +4 more
core  

An All‐Soft Wearable Electrochemiluminescence Chip for Sweat Metabolite Detection

open access: yesAdvanced Science, EarlyView.
A wearable electrochemiluminescence chip for sweat metabolite monitoring is pioneered, integrating “all‐soft” components: a flexible closed bipolar electrode (c‐BPE) array based on laser‐induced graphene (LIG), a laser‐cut microfluidic layer for sweat collection, and deep eutectic solvents (DES)‐based conductive ionogels for ECL emission.
Wei Nie   +7 more
wiley   +1 more source

Review on flow separation control: effects of excitation frequency and momentum coefficient

open access: yesFrontiers in Mechanical Engineering
This paper presents a comprehensive review of the studies and research conducted on flow separation control on lifting surfaces. In this paper, two critical parameters, namely, the momentum coefficient and excitation frequency, that significantly impact ...
Soheila Abdolahipour
doaj   +1 more source

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

open access: yesAdvanced Science, EarlyView.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong   +5 more
wiley   +1 more source

A Numerical Investigation of Film Cooling under the Effects of Different Adverse Pressure Gradients

open access: yesAerospace
Film cooling needs to be applied to serpentine nozzles due to an increase in thermal load. Adverse pressure gradients (APGs) near the upper wall of such nozzles hinder the forward flow of the coolant, and they may even induce a recirculation zone that ...
Jingwei Shi   +4 more
doaj   +1 more source

Ultrafast Multilevel Switching and Synaptic Behavior in a Planar Quantum Topological Memristor

open access: yesAdvanced Science, EarlyView.
Dry‐transferred Bi2Te3 layers enable a planar quantum topological memristor framework. In‐plane topological surface states facilitate ultrafast & low‐power operations. Coexisting analog and digital modes support current‐controlled multilevel states. PQTM exhibits 105 s retention, 103 cycles endurance, and reproducibility across 24 devices.
Mamoon Ur Rashid   +12 more
wiley   +1 more source

Upper-surface blowing nacelle design study for a swept wing airplane at cruise conditions [PDF]

open access: yes
A study was made to design two types of overwing nacelles for an existing wing-body at a design condition of Mach = 0.8 and C sub L = 0.2. Internal and external surface contours were developed for nacelles having either a D-shaped nozzle or a high-aspect-
Gillette, W. B.   +3 more
core   +1 more source

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