Results 41 to 50 of about 474,679 (251)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Aboveground biomass growth mapping and CO2 uptake of multispecies seagrass meadow in Menjangan Besar Island, Karimunjawa Islands, using Sentinel-2 imagery

open access: yesOceanological and Hydrobiological Studies
Seagrasses absorb CO2 for photosynthesis and convert it into new biomass. This study aims to assess the correlation between seagrass aboveground biomass (AGB) growth and percent cover, map and analyse AGB growth using Sentinel-2 imagery and estimate CO2 ...
Putri Aurellia Devina   +1 more
doaj   +1 more source

The Blue Carbon Protection System in the Marine Environmental Protection Law of the People's Republic of China

open access: yesHaiyang Kaifa yu guanli, 2023
Blue carbon is an important driver to achieve the "carbon peak" and "carbon neutrality" goals in China and promote the development of the national carbon market.
Shuai FENG, Junchao LIAO
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Advantages,Challenges and Countermeasures of Developing Coastal Blue Carbon Sink in China in the Background of Carbon Neutrality

open access: yesHaiyang Kaifa yu guanli, 2023
Coastal blue carbon plays an important role in the global climate change and carbon cycle. Ecological restoration and market trading can effectively improve coastal blue carbon sink, which is a cost-effective way to achieve carbon neutrality. In order to
Hao CHENG   +4 more
doaj  

Blue Laser for Production of Carbon Dots

open access: yesPolymers
The synthesis of carbon dots (CDs) is gaining wide-ranging interest due to their broad applicability, owing to their small size and luminescence. CDs were prepared from charcoal via a one-step process using laser ablation in liquid without the use of reagents.
Mariapompea Cutroneo   +3 more
openaire   +5 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Blue carbon in sediment from Sanggou Bay: composition, burial flux and its response to human activities

open access: yesFrontiers in Marine Science
Marine primary production and terrestrial input are the main sources of buried carbon in sediments of marginal seas. Only marine-source carbon buried in sediments, fixed and stored by marine ecosystems, belongs to “blue carbon” and reflects marine ...
Shu Yang   +10 more
doaj   +1 more source

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