Results 71 to 80 of about 508,541 (277)

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan   +14 more
wiley   +1 more source

Preliminary report of improved sleep quality in patients with dry eye disease after initiation of topical therapy

open access: yesNeuropsychiatric Disease and Treatment, 2016
Masahiko Ayaki,1 Ikuko Toda,2 Naoko Tachi,3 Kazuno Negishi,1 Kazuo Tsubota11Department of Ophthalmology, Keio University School of Medicine, 2Department of Ophthalmology, Mimamiaoyama Eye Clinic, Tokyo, 3Eye Center, Shinseikai Toyama Hospital ...
Ayaki M   +4 more
doaj  

Factors Influencing Optical Coherence Tomography Peripapillary Choroidal Thickness: A Multicenter Study. [PDF]

open access: yes, 2019
Purpose:To quantify peripapillary choroidal thickness (PCT) and the factors that influence it in healthy participants who represent the racial and ethnic composition of the U.S. population.
Burgoyne, Claude F   +14 more
core  

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

Development of a loop-mediated isothermal amplification assay for rapid detection of African swine fever

open access: yesVeterinary Integrative Sciences, 2020
Since the first African swine fever (ASF) outbreak was reported in China in 2018, the disease has spread rapidly to several countries in Asia. The early detection of this disease is essential for the ASF control strategy to be effective.
Arphaphorn Dokphut   +3 more
doaj   +1 more source

Multispectral oximetry of murine tendon microvasculature with inflammation [PDF]

open access: yes, 2017
We report a novel multispectral imaging technique for localised measurement of vascular oxygen saturation (SO2) in vivo. Annular back-illumination is generated using a Schwarzchild-design reflective objective.
Brewer, James M   +2 more
core   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights from a large international sicca registry

open access: yesArthritis Care &Research, Accepted Article.
Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni   +7 more
wiley   +1 more source

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins [PDF]

open access: yes, 2014
An expanded GGGGCC repeat in C9orf72 is the most common genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis. A fundamental question is whether toxicity is driven by the repeat RNA itself and/or by dipeptide repeat proteins ...
Cabecinha, M   +19 more
core   +1 more source

Anomalous Pressure‐Temperature Ultrahigh Sensitivities in Atomically Engineered Carbonitride MXenes for Multifunctional Wearable Human–Machine Interfaces: Joint Computational–Experimental Elucidations

open access: yesAdvanced Functional Materials, EarlyView.
Atomically engineered layered 2D Ti3CNTz carbonitride MXene exhibits ultrahigh heat and pressure sensitivity, enabling dual‐mode sensors with 300%–400% performance enhancement and durability for real‐time health‐monitoring interface devices. Precise nitrogen incorporation (e.g., Ti3C1.8N0.2Tz) boosts conductivity, enhancing temperature response, while ...
Debananda Mohapatra   +12 more
wiley   +1 more source

‘BLUES’ procedure for assessing the blue level of the sclera in Osteogenesis Imperfecta

open access: yesOrphanet Journal of Rare Diseases
Purpose Blue sclera is a characteristic and common clinical sign of Osteogenesis Imperfecta (OI). However, there is currently no widely accepted, objective method for assessing and grading blue sclera in individuals with OI. To address this medical need,
Valerio Di Martino   +8 more
doaj   +1 more source

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