Results 81 to 90 of about 6,322,087 (352)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Comparison of blue light-filtering IOLs and UV light-filtering IOLs for cataract surgery: a meta-analysis.

PLoS ONE, 2012
BackgroundA number of published randomized controlled trials have been conducted to evaluate visual performance of blue light-filtering intraocular lenses (IOL) and UV light-filtering intraocular lenses (IOL) after cataract phacoemulsification surgery ...
Xiao-feng Zhu, Hai-dong Zou, Yong-fu Yu, Qian Sun, Nai-qing Zhao   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Suppression of Blue Light at Night Ameliorates Metabolic Abnormalities by Controlling Circadian Rhythms.

Investigative Ophthalmology and Visual Science, 2019
Purpose Light-emitting diodes that emit high-intensity blue light are associated with blue-light hazard. Here, we report that blue light disturbs circadian rhythms by interfering with the clock gene in the suprachiasmatic nucleus (SCN) and that ...
N. Nagai, M. Ayaki, T. Yanagawa, A. Hattori, K. Negishi, Takuro Mori, Takahiro J. Nakamura, K. Tsubota   +7 more
semanticscholar   +1 more source

Blue-Light-Excitable, Quantum Yield Enhanced, Yellow-Emitting, Zirconium-Based Metal–Organic Framework Phosphors Formed by Immobilizing Organic Chromophores

, 2019
We demonstrate that two new zirconium-based metal–organic frameworks can be constructed from organic chromophore ligands. Both compounds show intense yellow emission when excited by blue light, with a notable fluorescence red shift and quantum yield ...
Jing Li (10611), Liang Yu (207992), Simon J. Teat (1304670), Wei Liu (20030), Hao Wang (39217)   +4 more
core   +1 more source

RGB generation by four-wave mixing in small-core holey fibers [PDF]

, 2007
We report the generation of white light comprising red, green, and blue spectral bands from a frequency-doubled fiber laser by an efficient four-wave mixing process in submicron-sized cores of microstructured holey fibers.
Horak, P., David J. Richardson, Nilsson, J., Dupriez, P., Richardson, D.J., Poletti, F., Johan Nilsson, David N. Payne, Marco N. Petrovich, Pascal Dupriez, Payne, D.N., Petrovich, M.N., Jeong, Y., Yoonchan Jeong, Peter Horak, Francesco Poletti   +15 more
core   +1 more source

Integrated transcriptome and metabolome analysis provides insights into blue light response of Flammulina filiformis

AMB Express
Blue light promotes primordium differentiation and fruiting body formation of mushroom. However, the blue light response mechanism of mushroom remains unclear. In this study, mycelium of Flammulina filiformis was exposed to blue light, red light and dark
Huan Wang, Shuting Zhao, Zhiyang Han, Zexin Qi, Lei Han, Yu Li   +5 more
doaj   +1 more source

Blue Light Sensing in Listeria monocytogenes Is Temperature-Dependent and the Transcriptional Response to It Is Predominantly SigB-Dependent

Frontiers in Microbiology, 2019
Listeria monocytogenes is an important food-borne pathogen that is tolerant to many of the stresses commonly used during food preservation. Outside the host, the bacterium has a saprophytic lifestyle that includes periodic exposure to solar irradiance ...
Amber L. Dorey, Bo-Hyung Lee, Bjorn Rotter, Conor P. O’Byrne   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

On the photosynthetic and devlopmental responses of leaves to the spectral composition of light

, 2010
Key words: action spectrum, artificial solar spectrum, blue light, Cucumis sativus, gas-exchange, light-emitting diodes (LEDs), light interception, light quality, non-photosynthetic pigments, photo-synthetic capacity, photomorphogenesis, photosystem ...
Hogewoning, S.W.
core