Results 81 to 90 of about 1,928,900 (335)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Symmetric Responses to Diet by Plumage Carotenoids in Violet-Sensitive Piciform–Coraciiform Birds

Diversity
Biological studies on symmetry can be expanded to consider red (longer wavelengths) and blue (shorter wavelengths) shifts as antisymmetries (opposite-pattern symmetries), which may arise from similar underlying causes (invariant process symmetries).
Robert Bleiweiss
doaj   +1 more source

Sensing Characteristics of Side-Hole Fiber-Based Long-Period Grating

Advances in Materials Science and Engineering, 2013
Long-period gratings (LPGs) have been fabricated in a side-hole fiber (SHF) by using a pulsed CO2 laser. Sensing characteristics of this SHF-LPG to temperature surrounding refractive index and bend have been investigated.
Yi Xin, Xinyong Dong, Junwei Yuan, Yi Li, Shangzhong Jin, Sulei Zhang   +5 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Effect of Native Defects on Optical Properties of InxGa1-xN Alloys

, 2005
The energy position of the optical absorption edge and the free carrier populations in InxGa1-xN ternary alloys can be controlled using high energy 4He+ irradiation.
Ager III, J. W., Haller, E. E., Li, S. X., Lu, Hai, Schaff, William J., Shan, W., Walukiewicz, W., Wu, J., Yu, K. M.   +8 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

blue shift

, 2014
Citation: 'blue shift' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.B00688 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Ferromagnetic resonance of a two-dimensional array of nanomagnets: Effects of surface anisotropy and dipolar interactions

, 2018
We develop an analytical approach for studying the FMR frequency shift due to dipolar interactions and surface effects in two-dimensional arrays of nanomagnets with (effective) uniaxial anisotropy along the magnetic field.
Déjardin, J. -L., Franco, A. F., Kachkachi, H., Vernay, F.   +3 more
core   +2 more sources