Results 151 to 160 of about 16,936 (254)

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

open access: yesJournal of Applied Toxicology, Volume 46, Issue 11, Page 4076-4084, November 2026.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos   +4 more
wiley   +1 more source

A survey of blue-stain fungi in Northwestern Ontario and characterization of mobile introns in ribosomal DNA

open access: yes, 2011
This work presents a survey of blue-stain fungi found in Northwestern Ontario, characterization of a homing endonuclease gene within Grosmannia piceiperda and finally an examination of the introns and homing endonuclease genes found in the large ribosomal subunit gene in species of Ceratocystis; using molecular techniques and phylogenetic analysis, we ...
openaire   +1 more source

Novel Carbazole–Acylthiourea Derivatives: Synthesis, Antimicrobial, Antioxidant, Hemocompatibility, Cytotoxicity, and ADME‐Tox Profiling

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
We synthesized four novel carprofen‐derived carbazole–acylthiourea propanamides with selective antimicrobial activity against Staphylococcus aureus, Enterococcus faecalis, and Candida albicans. Compound 1a provides combined antioxidant and antihemolytic protection.
Carmen Limban   +17 more
wiley   +1 more source

Evaluating Harm Reduction Advice From Large Language Models

open access: yesDrug and Alcohol Review, Volume 45, Issue 7, November 2026.
ABSTRACT Introduction Large language models (LLM) and generative Artificial Intelligence are increasingly providing health information. We have applied a novel method to evaluate the harm reduction information generated by popular LLMs. We focused on the filtration of oral medications for injection and the availability of local harm reduction services.
Khy Choo   +3 more
wiley   +1 more source

Temperature, Disinfectant Concentration and Bacterial Innate Properties Influence the Disinfection of Bacterial Pathogens Relevant to Catfish Aquaculture

open access: yesJournal of Fish Diseases, Volume 49, Issue 11, November 2026.
ABSTRACT Aquaculture systems suffer a wide range of losses, mostly due to bacterial disease outbreaks, and the use of disinfectants is a routine practice for controlling the spread of pathogenic organisms globally. Including Aeromonas hydrophila, Streptococcus agalactiae and Edwardsiella tarda, implicated for natural disease outbreaks and economic ...
Aloysius Chimezie Adibe   +1 more
wiley   +1 more source

High‐variance phenome database reveals important roles of WD40 proteins in the plant pathogenic fungus Fusarium graminearum

open access: yesNew Phytologist, Volume 252, Issue 3, Page 1215-1231, November 2026.
Functional analysis of predicted interaction‐associated WD40 blades in Fgwd101 and Fgwd048 of Fusarium graminearum. Summary WD40 is a highly conserved protein domain in eukaryotes that functions as a versatile platform for protein–protein interactions and participates in diverse biological processes.
Soyoung Choi   +15 more
wiley   +1 more source

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