Results 191 to 200 of about 36,167 (307)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Acoustic Analysis of Blues, Country, Folk, Italian Opera, and Rock Singing. [PDF]

J Voice
Bienhold GJ, Meyer DP, Wischhoff OP, Chumbley TJ, Heimer EO, Moreira EA, Jiang J.   +6 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

OzBarley: A genetic and phenotypic data resource capturing the Australian barley breeding history. [PDF]

Sci Data
Baumann U, Kalashyan E, Schwerdt J, Box A, Brien C, Chalmers K, Coventry S, Ganesalingam A, Hyles J, Lobsey B, Lou H, Raubach S, Richmond S, Sainsbury G, Shaw PD, Sherman B, Stephen JR, Trevaskis B, Waugh R, Tucker MR, Berger B.   +20 more
europepmc   +1 more source

Looking Ahead: Coastal Jazz & Blues Society's Newsletter

, 1994

core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Predictors of post-partum depression amongst postnatal women in Kumasi, Ghana. [PDF]

BMC Pregnancy Childbirth
Emikpe AO, Obeng H, Bonsu ZM, Tsiko EA, Owusu LB, Dwumfour CK, Issifu JS, Dzomeku VM.   +7 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Targeted expansion of a barley genebank core collection facilitates the discovery of disease resistance loci. [PDF]

Theor Appl Genet
Yuan Z, Zhao Y, Oldach K, Jahoor A, Jensen JD, Dohrendorf VE, Eschholz TW, Roescher S, Stein N, Reif JC, El Hanafi S.   +10 more
europepmc   +1 more source

Looking Ahead: Coastal Jazz & Blues Society's Newsletter

, 1992

core