Results 231 to 240 of about 36,167 (307)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Harnessing historical genebank data to accelerate pea breeding. [PDF]

Theor Appl Genet
Niels L, Reif JC, Otto LG, Mirdita V, Oppermann M, Lohwasser U, Kotter M, Weise S, El Hanafi S.   +8 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Order from entropy: big data from FAIR data cohorts in the digital age of plant breeding. [PDF]

Theor Appl Genet
Gogna A, Arend D, Beier S, Rezaei EE, Würschum T, Zhao Y, Chu J, Reif JC.   +7 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Exploring standing genetic variation for barley leaf rust resistance in Australian breeding panel. [PDF]

Theor Appl Genet
Pandit M, Dracatos P, Periyannan S, Lam Y, Brunner SM, Honse T, Tong J, Dinglasan E, Ganesalingam D, Moody D, Baraibar S, Hickey L, Alahmad S, Robinson H.   +13 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Maternal health workers' knowledge, practices, and influencing factors in screening and managing perinatal mental health conditions in primary healthcare facilities in Addis Ababa, Ethiopia: a qualitative study. [PDF]

BMC Health Serv Res
Bimrew M, Field S, Beňová L, Meudec M, Gebremedhin S, Workicho A, Bekele D, Alamdo AG, Asefa A.   +8 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Dishwashing liquids with nuclease and protease: An improved biocompatible solution for the removal of adherent bacteria from fruits and vegetables. [PDF]

AIMS Microbiol
Ayzatullina L, Kolyshkina S, Patronova E, Filatov V, Zadorina I, Kharitonova M, Bogachev M, Kayumov A.   +7 more
europepmc   +1 more source