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The Replication of Bluetongue Virus

1990
Bluetongue virus (BTV) replicates in the cytoplasm of a wide variety of cell types and infection ultimately leads to cell death. The studies of Verwoerd, Huismans and others in the late 1960s and continuing to the present (see Chap. 2, this volume) on the double-stranded, segmented genomic RNA (Verwoerd 1969; Verwoerd et al. 1970), the bishelled nature
B T, Eaton, A D, Hyatt, S M, Brookes
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Nontransmission of bluetongue virus by embryos from bluetongue virus-infected sheep

American Journal of Veterinary Research, 1988
SUMMARY Donor sheep were infected either by bites of bluetongue virus (btv)-infected (serotype 11, “Texas Station strain”) Culicoides variipennis or by inoculation with 100,000 median chicken embryo intravascular lethal doses of btv (serotype 11) from a suspension made from infected C variipennis.
W C, Hare   +7 more
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Bluetongue Virus

Veterinary Clinics of North America: Food Animal Practice, 1994
Bluetongue (BLU) is a noncontagious viral disease. The virus is a member of the Orbivirus genus and serves as the prototype virus of the genus. BLU is primarily a disease of domestic ruminants, some wild ruminants, and, recently, domestic dogs. The disease is caused by 1 of 24 different serotypes of virus that are distributed worldwide.
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No evidence of bluetongue virus in Switzerland

Veterinary Microbiology, 2006
We report the results of the first survey for antibody against bluetongue virus (BTV) that was conducted in Switzerland in the year 2003. In a nationwide cross-sectional study with partial verification, 2437 cattle sera collected from 507 herds were analysed using competitive enzyme-linked immunosorbent assays (c-ELISA). To adjust for misclassification,
A, Cagienard   +4 more
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Caprine Bluetongue Virus Isolations

American Journal of Veterinary Research, 1980
SUMMARY Viral isolation procedures demonstrated the presence of bluetongue virus serotypes 10, 11, and 17 in routine caprine accessions. The goats in this report showed one or more of the following signs or lesions: weakness, pulmonary disease, abortion, fetuses with developmental abnormalities, kerato-conjunctivitis, anemia, and swollen joints.
M, Inverso, G N, Lukas, S J, Weidenbach
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Bluetongue Virus in Pronghorn Antelope

American Journal of Veterinary Research, 1972
SUMMARY Four adult pronghorn antelope (Antilocapra americana) were inoculated subcutaneously with bluetongue virus (btv) strain BT-8. Two antelope which did not possess preinoculation btv neutralizing antibodies developed clinical signs of bluetongue (bt) and died 7 and 8 days after inoculation. A low-level viremia persisted in each antelope for 3 days
G L, Hoff, D O, Trainer
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Bluetongue Virus in Exotic Ruminants

Journal of the American Veterinary Medical Association, 1973
SUMMARY An epizootic of a hemorrhagic disease occurred in 6 species of exotic ruminants at the San Diego Zoo and San Diego Wild Animal Park in 1970 and 1971. The disease was reproduced in deer by inoculation of pericardial and pleural fluids from a muntjac (Muntiacus reeuesi) and the spleen of a kudu (Tragelaphus capensis). The agent was also recovered
G L, Hoff, L A, Griner, D O, Trainer
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Bluetongue Virus Structural Components

1990
The structural components of bluetongue virus (BTV), the prototype of the orbivirus genus, has been the subject of a number of reviews (Verwoerd et al. 1979; Gorman and Taylor 1985; Spence et al. 1984). The main features can be summarized as follows: BTV is an icosahedral-shaped particle consisting of a segmented double-stranded RNA genome encapsidated
H, Huismans, A A, Van Dijk
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Association of bluetongue virus with the cytoskeleton

Virology, 1987
Analysis of the distribution of [35S]methionine-labeled virus proteins following lysis of bluetongue virus (BTV)-infected cells with nonionic detergents showed that a major proportion of the virus-specific proteins was located in the insoluble nuclear-cytoskeletal fraction.
B T, Eaton, A D, Hyatt, J R, White
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Purification and characterization of bluetongue virus

Virology, 1969
Abstract Purified bluetongue virus was shown to possess a double-stranded RNA genome, very similar to that of reovirus, consisting of at least three double-stranded components. A low molecular weight component probably equivalent to the adenine-rich single strand found in reovirus was present in varying amounts.
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