Results 171 to 180 of about 578,151 (361)
Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis
Advanced Science, EarlyView.Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu +13 more
wiley +1 more source
On radiative transfer in the low Reynolds number blunt body stagnation region at hypersonic speeds. Part 1 - Emission dominated case [PDF]
Effect of radiative heat transfer in low Reynolds number hypersonic flow about blunt ...
Liu, J. T. C.
core +1 more source
ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling
Advanced Science, EarlyView.ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao +19 more
wiley +1 more source
Facial Skin Revitalization With CPM-HA20G (Hyaluronic Acid + Glycerol): A Comparative Case Series Using Three Delivery Techniques With Ultrasound Confirmation. [PDF]
J Cosmet DermatolBooysen K, Lin F.
europepmc +1 more source
Ionization of air in flow around a blunt wedge at relatively low hypersonic speeds
, 2018 С. Т. Суржиков
openalex +1 more source
Advanced Science, EarlyView.Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang +12 more
wiley +1 more source
Blunt versus sharp expansion of uterine incision during lower segment cesarean section. [PDF]
BMC Pregnancy ChildbirthZeinhom AM, Habib SM, Atta AE, Essam AM.
europepmc +1 more source
Viscous compressible flow about blunt bodies using a numerically generated orthogonal coordinate system [PDF]
A numerical solution to the Navier-Stokes equations was obtained for blunt axisymmetric entry bodies of arbitrary shape in supersonic flow. These equations are solved on a finite difference mesh obtained from a simple numerical technique which generates ...
Graves, R. A., Jr., Hamilton, H. H., II
core +1 more source