Results 121 to 130 of about 139,468 (361)
Advanced Science, EarlyView.Granular hydrogels are being developed for the repair of tissues, mostly with the use of spherical microgels. Here, injectable granular hydrogels formed from anisotropic particles (i.e., rod‐like) are explored to improve cellular invasion by increasing scaffold void volume fraction.
Gabriel J. Rodriguez‐Rivera +11 more
wiley +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
Hepatology, EarlyView., 2022 In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source
Intracellular Mechanical Stress‐Mediated Autophagy Cell Death via Nanospikes for Cancer Treatment
Advanced Science, EarlyView.Nanospikes with tunable morphology at the nanoscale induce lysosomal membrane damage by generating localized mechanical stress, activating Galectin‐3 (Gal3)‐Trim16‐mediated autophagic cell death. Finite element analysis and laser‐triggered spike ablation enable precise control of intracellular force signaling and cytotoxicity, offering a ...
Yingze Li +11 more
wiley +1 more source
Hepatology, EarlyView., 2022 CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source
Bildediagnostikk av traumatisk diafragmaruptur [PDF]
, 2008 Background: Diaphragmatic injury is an uncommon result of blunt and penetrating trauma. To recognize this injury, the radiologist must be familiar with the imaging manifestations of the injury.
Skjellegrind, Erik Kjesbu
core
Advanced Science, EarlyView.A selenomethionine‐derived carbon dot (Se‐Met‐CD) serves as a potent nano‐antioxidant, efficiently scavenging reactive oxygen species, protecting nucleus pulposus cells from oxidative damage, restoring extracellular matrix homeostasis, and significantly mitigating intervertebral disc degeneration in vivo, which demonstrates great promise as a nanozyme ...
Qingzheng Zhang +4 more
wiley +1 more source
Coronary artery-left ventricular fistula and multiple ventricular septal defects due to blunt chest trauma. [PDF]
, 1989 Attilio Renzulli +2 more
openalex +1 more source
Abdominal intercostal hernia: a rare complication after blunt trauma. [PDF]
, 2013 Abdominal intercostal hernia (AIH) is uncommonly reported in the literature with only 20 cases reported to date.1–3 We report a case of a delayed incarcerated AIH secondary to blunt trauma from a motor vehicle accident in which the colon and diaphragm ...
Cowan, MD, Scott W. +3 more
core +1 more source
American Journal of Community Psychology, EarlyView.Abstract Violent injuries tend to cluster together geospatially. The discriminatory housing practice of redlining undertaken by the United States federal government in the 1930s has been repeatedly linked with various contemporary community‐level disparities.
Samuel J. West +5 more
wiley +1 more source
The Role of Computed Tomography in Blunt Abdominal Trauma
Journal of Nepal Medical Association, 2016 Introduction: Blunt injury trauma is regularly encountered in the emergency department. Diagnostic tools that help in optimum management of blunt abdominal trauma include; Focussed Assessment Sonography for Trauma scan, Diagnostic peritoneal lavage and ...
Om Bahadur Karki
doaj