Results 61 to 70 of about 115,104 (244)

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

Advanced Science, EarlyView.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li, Xinran Dong, Kexing Gao, Yiyang Wang, Min Li, Huayun Deng, Shuangyu Ma, Yaping Lv, Wei Jin, Quanfu Li, Yuming Wang, Xiaodong Liao, Kangjing Bian, Aiwu Zhou, Chengping Hu, Lei Huang   +15 more
wiley   +1 more source

Assembling Hexahedral Supramolecular Nano‐Aggregates on Rice Wax Layer Matrices to Promote the Leaf Deposition and Bioavailability of Bactericides for Plant Protections

Advanced Science, EarlyView.
To address the problem of off‐target movement and low bioavailability of pesticides, two anisotropic supramolecular building units (BiTA18@β‐CD and BiTA18@γ‐CD) have been invented that can self‐assemble into nano‐sized hexagonal cuboids on the rice microcrystalline matrix. This manipulation realizes the enhanced utilization of bactericides for rice and
Run Yang, Jinghan Yang, Min Liu, Juan Liu, Peiyi Wang   +4 more
wiley   +1 more source

Incidence and outcomes of major trauma assaults: a population-based study in Victoria

, 2009
OBJECTIVE: To describe the incidence and outcomes of assault resulting in serious injury in Victoria. DESIGN AND SETTING: Analysis of population-based data from the Victorian State Trauma Registry for assaults between 1 July 2001 and 30 June 2007.
Cameron, Peter A., Gabbe, Belinda J., Mikocka-Walus, Antonina A., O\u27Mullane, Phebe A.   +3 more
core  

Psychological Barriers in Long Term Non-Operative Treatment of Retroperitoneal Hematoma [PDF]

, 2015
The retroperitoneal hematoma can have, mainly, a traumatic etiology - blunt abdominal trauma (falls from height, road accidents, aggression of any kind, etc.), or open (incised wounds, puncture, penetration or gunshot wounds). Ruptured arterial aneurysms
Bobic, Simona, Carȃp, Alexandru, Constantin, Vlad Denis, Socea, Bogdan   +3 more
core   +3 more sources

Hypothenar Hammer Syndrome in a Postal Worker [PDF]

, 2008
We present the case of a 48-year-old woman with hypothenar hammer syndrome. Hypothenar hammer syndrome is caused by chronic repetitive trauma to the ulnar artery and superficial palmar arch.
Dunkin, Jared, Gilet, Anthony, Gould, Elaine   +2 more
core   +1 more source

A multicenter randomized controlled trial evaluating the effect of the use of an anti‐adhesion barrier for diverting ileostomy on the multidimensional workload in minimally invasive surgery for rectal cancer (YCOG 2005: The ADOBARRIER study)

Annals of Gastroenterological Surgery, EarlyView.
This multicenter, single‐blind, randomized, controlled trial was conducted to evaluate the multidimensional workload of the first operator during ileostomy closure using the SURG‐TLX between groups with and without the use of the spray‐type anti‐adhesion material during diverting ileostomy construction.
Emi Ota, Jun Watanabe, Yusuke Suwa, Masakatsu Numata, Hirokazu Suwa, Hiroki Ohya, Kazuya Nakagawa, Mayumi Ozawa, Itaru Endo   +8 more
wiley   +1 more source

Computed tomography (CT) in blunt liver injury: a pictorial essay [PDF]

, 2010
Computed tomography (CT) is widely used in assessing clinically stable patients with blunt abdominal trauma. In these patients, liver is one of the commonest organs being injured and CT can accurately identify and assess the extent of the injury.
Abd. Aziz, Azian, Che Mohamed, Siti Kamariah, Hassan, Radhiana, Md Ralib @ Md Raghib, Ahmad Razali   +3 more
core  

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin‐Independent Regulation of Fpn mRNA

American Journal of Hematology, EarlyView.
ABSTRACT The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) by inhibiting the iron exporter ferroportin in target cells, causing hypoferremia. Under acute inflammation, hepcidin induction requires hemojuvelin (Hjv), a bone morphogenetic protein co‐receptor, while Fpn mRNA is also suppressed in a hepcidin‐
Siqi Liu, Sofiya Tsyplenkova, Carine Fillebeen, Kostas Pantopoulos   +3 more
wiley   +1 more source

Beyond administrative burden: Activation and administrative harm

Australian Journal of Social Issues, EarlyView.
Abstract Within recent public policy and administration scholarship, there has been a growing focus on the concept of “administrative burden” to describe the learning, compliance and psychological costs incurred by citizens when trying to access services and exercise social and political rights. Specifically, in the context of activation and welfare‐to‐
Michael McGann, Sarah Ball
wiley   +1 more source

3‐Year Outcomes of Temperature‐Controlled Radiofrequency Ablation of the Posterior Nasal Nerve in Patients With Chronic Rhinitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Temperature‐controlled radiofrequency (TCRF) ablation of the posterior nasal nerve has been shown to improve chronic rhinitis (CR) symptoms and quality of life (QoL). This study assesses the durability of TCRF's effectiveness and safety 3 years post‐procedure in patients with perennial allergic CR and nonallergic CR.
J. Pablo Stolovitzky, Randall A. Ow, Stacey L. Silvers, Bobby A. Tajudeen, Chad M. McDuffie, Marc Dean, Ahmad R. Sedaghat, Katie Phillips, Masayoshi Takashima   +8 more
wiley   +1 more source