Results 141 to 150 of about 19,575 (260)

BLyS (TNFSF13B; BAFF) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Die vrou wat alleen bly (Karel Schoeman)

Tydskrif vir Letterkunde, 2019
Jacomien van Niekerk
doaj  

Perspectives on gender-inclusive language in Canadian sexual and reproductive health care: findings from a modified Delphi survey. [PDF]

BMC Health Serv Res
Goldberg JM, Thorne OG, Khan M, Kirubarajan A, Sloboda DM, Graybrook R, Barker LC, McKerracher L, Rathinappillai N, Tendland-Frenette MP, Vo T, Robertson Bly J, Murray-Davis B.   +12 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Pituitary Stalk Lesion Sampling by Transsphenoidal Posterior Lobe Biopsy: A Case Series. [PDF]

J Neurol Surg B Skull Base
Hiatt K, Abecassis ZA, Eaton J, Hanks T, Raub S, Baird-Daniel E, Zhao Z, El-Ghazali F, Nistal D, Jamshidi A, Hartl K, Child D, Lee A, Bly R, Ferreira M, Ruzevick J, Emerson S.   +16 more
europepmc   +1 more source

Implementing a "Distance Traveled" Question to Improve Resident Diversity: Process and Feasibility. [PDF]

OTO Open, 2022
Epstein S, Konuthula N, Meyer TK, Whipple ME, Bowe SN, Bly RA, Abuzeid WM.   +6 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Editorial. [PDF]

Radiat Prot Dosimetry
Forssell-Aronsson E, Bernhardsson C.
europepmc   +1 more source