Results 221 to 230 of about 19,575 (260)
Some of the next articles are maybe not open access.
Biotechnology Letters, 2012
B lymphocyte stimulator (BLyS) antagonists are new therapeutic reagents for treating the autoimmune diseases. Peptibodies can inhibit the bioactivity of BLyS, the same as other BLyS antagonists: decoyed BLyS receptors and anti-BLyS antibodies. In this study, a new optimized BLyS antagonist peptide was designed according to our previous work by the ...
Yu, Tian +6 more
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B lymphocyte stimulator (BLyS) antagonists are new therapeutic reagents for treating the autoimmune diseases. Peptibodies can inhibit the bioactivity of BLyS, the same as other BLyS antagonists: decoyed BLyS receptors and anti-BLyS antibodies. In this study, a new optimized BLyS antagonist peptide was designed according to our previous work by the ...
Yu, Tian +6 more
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Structural basis of BLyS receptor recognition
Nature Structural Biology, 2002B lymphocyte stimulator (BLyS), a member of the tumor necrosis factor (TNF) superfamily, is a cytokine that induces B-cell proliferation and immunoglobulin secretion. We have determined the three-dimensional structure of BLyS to 2.0 A resolution and identified receptor recognition segments using limited proteolysis coupled with mass spectrometry ...
Deena A, Oren +8 more
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Targeting BLyS in Systemic Lupus Erythematosus
Recent Patents on Inflammation & Allergy Drug Discovery, 2012Systemic lupus erythematosus (SLE) is a chronic disabling autoimmune disease that significantly impacts the quality of life of patients, and can associate with several complications including end-stage renal disease and shortened lifespan. A central component in the pathogenesis of SLE is the B-cell production of autoantibodies to multiple self ...
Yaoyang, Liu, Antonio, La Cava
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That Book Store in Bly Theville
Marketing Education Review, 2011Mary Gay Shipley built a charming business in Blytheville, Arkansas. She and her bookstore have a national reputation in the book world. Can That Bookstore in Blytheville leverage its reputation and charm into real profit?
Melodie Jordan Philhours +2 more
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BLyS antagonists and peptide tolerance induction
Lupus, 2005The major impediment to drug development for systemic lupus erythematosus (SLE) is its heterogeneity. The unpredictable manner in which lupus targets different organs at varying intensity makes the study of new drugs and the optimization of their administration extremely difficult.
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2008
Abstract Depression I felt my heart beat like an engine high in the air, Like those scaffolding engines standing only on planks; My body hung about me like an old grain elevator, Useless, clogged, full of blackened wheat. My body was sour, my life dishonest, and I fell asleep. I
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Abstract Depression I felt my heart beat like an engine high in the air, Like those scaffolding engines standing only on planks; My body hung about me like an old grain elevator, Useless, clogged, full of blackened wheat. My body was sour, my life dishonest, and I fell asleep. I
openaire +1 more source