Results 31 to 40 of about 649 (195)
Immunoglobulin Depletion and Recovery Following Blinatumomab in Infants With KMT2A‐Rearranged ALL
ABSTRACT Adding blinatumomab to standard chemotherapy for infants with KMT2A‐rearranged acute B‐cell lymphoblastic leukemia (KMT2A‐r B‐ALL) improves outcomes. Although blinatumomab impairs immunoglobulin G (lgG) production, increasing infection susceptibility, IgG recovery remains poorly understood.
Miguel Vieira Martins +14 more
wiley +1 more source
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
O código de conduta e ética das organizações é um instrumento que objetiva estruturar políticas e normas claras em relação ao comprometimento com os diferentes stakeholders. Nesse contexto, o objetivo desta pesquisa é analisar a estrutura e conteúdo dos
Aline Oliveira Araujo +2 more
doaj +1 more source
Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel +15 more
wiley +1 more source
ADERÊNCIA AO DISCLOSURE RELATIVO À AJUSTE A VALOR PRESENTE NAS EMPRESAS LISTADAS NA BM&FBOVESPA
A presente pesquisa teve dois objetivos principais: levantar os graus de cumprimento às orientações de divulgação definidas no CPC 12 pelas companhias listadas na Bolsa de Valores, Mercadorias e Futuros (BM&FBovespa); e identificar os incentivos capazes ...
Falber Cristiano Oliveira de Sousa +2 more
doaj +1 more source
Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
wiley +1 more source
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala +8 more
wiley +1 more source
O estudo objetivou analisar o grau de conformidade das informações divulgadas sobre ativos intangíveis em empresas da BM&FBovespa, por meio de um índice de evidenciação elaborado com base no CPC 04. Para tal, realizou-se pesquisa descritiva, documental e
Geovanne Dias de Moura +1 more
doaj
O objetivo do artigo é analisar o nível de disclosure nos relatórios de sustentabilidade em conformidade com o Global Reporting Initiative (GRI) nas empresas listadas na BM&FBovespa.
Daniela Di Domenico +2 more
doaj +1 more source
The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi +7 more
wiley +1 more source

