Results 61 to 70 of about 649 (195)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
CONEXÕES POLÍTICAS NAS MAIORES COMPANHIAS LISTADAS NA BM&FBOVESPA
RESUMO As conexões políticas podem ser caracterizadas como relações entre empresas e políticos, em que as empresas procuram obter vantagens e os políticos geralmente buscam financiamento de campanha.
Bruno Goes Pinheiro +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
An Exploratory Study on the Complexity and Machine Learning Predictability of Stock Market Data. [PDF]
Raubitzek S, Neubauer T.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
THE USE OF DERIVATIVES IN THE INTERIMEDIARY FINANCIAL INSTITUTIONS LISTED ON BM & FBOVESPA
O presente trabalho teve como objetivo identificar variáveis que influenciam o uso de instrumentos financeiros derivativos pelas instituições intermediárias financeiras do Brasil listadas na BM&FBOVESPA, bem como identificar para qual finalidade estas instituições utilizam os instrumentos financeiros derivativos no período de 2006 a 2011.
Marques, Tatiane de Oliveira +1 more
openaire +1 more source
Nas últimas décadas, houve uma intensificação do processo de integração dos mercados de capitais no mundo, que gerou impactos profundos nas estratégias empresariais e facilitou o acesso ao capital internacional (Bell & Rasheed, 2016). Um dos instrumentos que está à disposição das empresas brasileiras e que visa facilitar a obtenção de recursos dos ...
Kuronuma, Cleiton Ricardo +2 more
openaire +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Combining Measures of Signal Complexity and Machine Learning for Time Series Analyis: A Review. [PDF]
Raubitzek S, Neubauer T.
europepmc +1 more source
The issuance of Brazilian Law 11.638/2007 is a critical step in the convergence of the Brazilian Generally Accepted Accounting Principles (GAAPs) towards International Financial Reporting Standards.
Fernando Drago Lorencini +1 more
doaj +1 more source

